Interval cancers and episode sensitivity in population-based screening programmes for colorectal cancer: a systematic review

Gaceta sanitaria
Xènia DomènechVíctor Moreno

Abstract

To describe interval cancers (IC) and the sensitivity of colorectal cancer (CRC) screening programmes. A systematic review of the literature was conducted through a MEDLINE (PubMed) search. The search strategy combined the terms 'interval cancer', 'false negative', 'mass screening', 'screening' 'early detection of cancer', 'colorectal cancer' and 'bowel cancer'. Inclusion criteria consisted of population-based screening programmes, original articles written in English or Spanish and publication dates between 1999/01/01 and 2015/02/28. A narrative synthesis of the included articles was performed detailing the characteristics of the screening programmes, the IC rate, and the information sources used in each study. Thirteen articles were included. The episode sensitivity of CRC screening programmes ranged from 42.2% to 65.3% in programmes using the guaiac test and between 59.1% and 87.0% with the immunochemical test. We found a higher proportion of women who were diagnosed with IC and these lesions were mainly located in the proximal colon. There is wide variability in the IC rate in CRC programmes. To ensure comparability between programmes, there is a need for consensus on the working definition of IC and the methods used for th...Continue Reading

References

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Jul 28, 2011·International Journal of Cancer. Journal International Du Cancer·Victoria S BensonUNKNOWN International Colorectal Cancer Screening Network
Jun 25, 2013·Gut·Douglas J RobertsonMaría Elena Martínez

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Citations

Jul 3, 2020·BMC Cancer·María Angeles Gutierrez-StampaLuis Bujanda
Aug 29, 2020·Cancers·María Angeles Gutierrez-StampaLuis Bujanda

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