Intervening sequences exhibit distinct vocabulary.

Journal of Biomolecular Structure & Dynamics
J S BeckmannE N Trifonov

Abstract

Little is known about the origin and function of eukaryotic introns. Application of a novel linguistic approach to the analysis of intervening sequences reveals, however, that they exhibit a specific non-random vocabulary whose major feature is the utilization of mirror-symmetrical words ("mirrorrim"). Introns also manifest a significant tendency to avoid local complementarities. Possible biological implications of the corresponding loop regions in the RNA transcripts are discussed.

References

Jan 1, 1979·Proceedings of the National Academy of Sciences of the United States of America·C J Lai, G Khoury
Sep 1, 1979·Proceedings of the National Academy of Sciences of the United States of America·P GrussG Khoury
Apr 20, 1979·Science·F Crick
Feb 9, 1978·Nature·W Gilbert
Nov 1, 1976·Journal of Molecular Biology·G J RussellJ H Subak-Sharpe
Sep 1, 1985·Cell·P A Sharp
May 23, 1985·Nature·T Cavalier-Smith
Aug 1, 1986·Journal of Biomolecular Structure & Dynamics·V BrendelE N Trifonov
May 17, 1985·Science·W Gilbert
Jan 11, 1980·Nucleic Acids Research·C BenoistP Chambon
Oct 1, 1980·Cell·R M LawnT Maniatis
Jan 22, 1982·Nucleic Acids Research·S M Mount
Dec 20, 1982·Nucleic Acids Research·G R Day, R D Blake
Dec 11, 1980·Nucleic Acids Research·A R Kimmel, R A Firtel

❮ Previous
Next ❯

Citations

Jan 1, 1989·Bulletin of Mathematical Biology·E N Trifonov
Oct 21, 1998·Molecular Biotechnology·J M Claverie
Jan 1, 1993·Bio Systems·M S Gelfand
Feb 14, 1998·Gene·E Zuckerkandl
Jun 1, 1990·Journal of Biomolecular Structure & Dynamics·S PietrokovskiE N Trifonov
Nov 24, 1999·Journal of Biomolecular Structure & Dynamics·D Häring, J Kypr
Jan 26, 2008·BMC Bioinformatics·Mark BauerKhalid Sayood
Mar 1, 2017·Parasitology·Michaela ZemkováJaroslav Flegr
Jan 1, 1995·Journal of Computational Biology : a Journal of Computational Molecular Cell Biology·S SchbathE de Turckheim
Jan 13, 2010·Bioinformatics and Biology Insights·Derek Gatherer

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.