May 24, 2011

Interventional endoscopic ultrasonography for pancreatic cancer

World Journal of Clinical Oncology
Kazuo HaraYasumasa Niwa

Abstract

Endoscopic ultrasonography (EUS) represents the combination of endoscopy and intraluminal ultrasonography. This allows use of a high-frequency transducer (5-20 MHz) that, due to the short distance to the target lesion, provides ultrasonographic images of higher resolution than those obtained from other imaging modalities, including multiple-detector-row-computed tomography, magnetic resonance imaging, and positron emission tomography. EUS is now a widely accepted modality for diagnosing pancreatic diseases. However, the most important limitation of EUS has been the lack of specificity in differentiating between benign and malignant changes. In 1992, EUS-guided fine needle aspiration (FNA) of lesions in the pancreas head was introduced into clinical practice, using a curved linear-array echoendoscope. Since then, EUS has evolved from EUS imaging to EUS-FNA and wider applications. Interventional EUS for pancreatic cancer includes EUS-FNA, EUS-guided fine needle injection, EUS-guided biliary drainage and anastomosis, EUS-guided celiac neurolysis, radiofrequency ablation, brachytherapy, and delivery of a growing number of anti-tumor agents. This review focuses on interventional EUS, including EUS-FNA and therapeutic EUS for pancrea...Continue Reading

Mentioned in this Paper

Endoscopy (Procedure)
Diagnostic Radiology Modality
Antineoplastic Agents
Anatomical Anastomosis
Magnetic Resonance Imaging
Positron-Emission Tomography
Pancreatic Carcinoma
Bulla
Pancreatitis
Neoplasms

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