Interventions for reducing inflammation in familial Mediterranean fever

The Cochrane Database of Systematic Reviews
Bin WuXi Yin

Abstract

Familial Mediterranean fever, a hereditary auto-inflammatory disease, mainly affects ethnic groups living in the Mediterranean region. Early studies reported colchicine as a potential drug for preventing attacks of familial Mediterranean fever. For those people who are colchicine-resistant or intolerant, drugs such as rilonacept, anakinra, etanercept, infliximab, thalidomide and interferon-alpha might be beneficial. To evaluate the efficacy and safety of interventions for reducing inflammation in people with familial Mediterranean fever. We used detailed search strategies to search the following databases: CENTRAL; MEDLINE; Embase; Chinese Biomedical Literature Database (CBM), China National Knowledge Infrastructure Database (CNKI); Wan Fang; and VIP. In addition, we also searched the clinical trials registries including ClinicalTrials.gov, the International Standard Randomized Controlled Trial Number Register, the WHO International Clinical Trials Registry Platform and the Chinese Clinical Trial Registry, as well as references listed in relevant reports.Date of last search: 21 May 2014. Randomized controlled studies of people with diagnosis of familial Mediterranean fever, comparing active interventions (including colchicine, ...Continue Reading

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Citations

Jan 28, 2016·The Cochrane Database of Systematic Reviews·Lars G HemkensMatthias Briel
Oct 20, 2018·The Cochrane Database of Systematic Reviews·Bin WuXi Yin

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