Interventions in aging and age-associated pathologies by means of nutritional approaches

Annals of the New York Academy of Sciences
Kenichi KitaniToshihiko Osawa

Abstract

So-called antioxidant strategies have not been shown convincingly to be effective in increasing life spans of animals. Thus, the general consensus of experimental gerontology in the last century was that the only reproducible means of prolonging survivals of animals is the calorie restriction paradigm. As a challenge against this dogma, we attempted to examine the effect of two potent antioxidants, one tetrahydrocurcumin (a biotransformed metabolite of curcumin contained in turmeric of Indian curry) and the other green tea polyphenols.

References

Jun 30, 1994·Annals of the New York Academy of Sciences·D Harman
Jun 1, 1996·Bioscience, Biotechnology, and Biochemistry·T YokozawaH Oura
Feb 1, 1997·Experimental and Toxicologic Pathology : Official Journal of the Gesellschaft Für Toxikologische Pathologie·T YokozawaH Oura
Jul 1, 1956·Journal of Gerontology·D HARMAN

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Citations

Mar 24, 2005·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Mette M Berger
Aug 17, 2006·Nutritional Neuroscience·Waleed M RennoSami Asfar
Apr 18, 2008·The Journal of Pharmacology and Experimental Therapeutics·Aynun N BegumSally A Frautschy
Mar 28, 2012·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Randy StrongDavid E Harrison
Nov 13, 2012·Experimental Gerontology·Bradley S FleenorDouglas R Seals
Aug 21, 2007·The Journal of Nutritional Biochemistry·Yuk Man LiZhen Yu Chen
Mar 15, 2016·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·Linda BingsohnAndreas Vilcinskas
Jan 17, 2019·Medicinal Research Reviews·Jan MartelJohn D Young
Apr 19, 2007·Molecular Nutrition & Food Research·Yuk Man LiZhen Yu Chen
Jun 2, 2017·Natural Products and Bioprospecting·Ai-Jun DingHuai-Rong Luo
Nov 15, 2018·CNS & Neurological Disorders Drug Targets·Fatma Tuğçe Gürağaç DereliEsra Küpeli Akkol

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