Interventions to facilitate return to work in adults with chronic non-malignant pain: a protocol for a systematic review and network meta-analysis.

BMJ Open
Mathilda BjörkElena Dragioti

Abstract

Work absenteeism due to chronic non-malignant pain (CNMP) is a major societal and individual cause of concern that requires effective treatments. We present a protocol for a systematic review and network meta-analysis (NMA) aiming to compare available interventions for return to work (RTW) in adults with CNMP. PubMed, Embase, PsycINFO, Web of Knowledge and Cochrane Central Register of Controlled Trials databases will be searched till 31 August 2020 for randomised controlled trials (RCTs) examining interventions for RTW outcomes among patients with CNMP. Two independent investigators will search the databases, perform data extraction and assess the methodological quality of the selected RCTs. The primary outcome will be RTW, if possible, full-time or part-time after work absence due to chronic pain from baseline to the last available follow-up. Secondary outcomes will include self-reported workability or work capacity, or self-reported physical functioning and quality of life as measured by any validated scale. Pairwise meta-analysis and NMA will be conducted for each outcome using a random-effects model. For the primary outcomes, we will also obtain the ranking of all competing interventions within each NMA using surface under ...Continue Reading

References

Sep 1, 1986·Controlled Clinical Trials·R DerSimonian, N Laird
Sep 6, 2003·BMJ : British Medical Journal·Julian P T HigginsDouglas G Altman
Nov 13, 2003·JAMA : the Journal of the American Medical Association·Walter F StewartRichard Lipton
Aug 13, 2005·European Journal of Pain : EJP·Harald BreivikDerek Gallacher
Nov 29, 2005·European Journal of Pain : EJP·Marina T van LeeuwenMichael J Cousins
Jul 10, 2007·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Ute BültmannNancy Carnide
Sep 18, 2007·European Journal of Pain : EJP·Jeanine A VerbuntJ André Knottnerus
Feb 21, 2009·Journal of Rehabilitation Medicine·Anders NorlundKristina Alexanderson
Jan 22, 2010·The Cochrane Database of Systematic Reviews·Frederieke SchaafsmaJos H Verbeek
Mar 10, 2010·Statistics in Medicine·S DiasA E Ades
Mar 25, 2011·Current Opinion in Supportive and Palliative Care·Ceri J Phillips, Christie Harper
Oct 8, 2011·BMC Public Health·Daniel S Goldberg, Summer J McGee
Mar 7, 2012·American Journal of Public Health·Sergio RuedaJohn Lavis
Apr 3, 2012·Pain Practice : the Official Journal of World Institute of Pain·Ajay S PatelJodie Barden
Sep 12, 2012·Lancet·Michael MarmotUNKNOWN Consortium for the European Review of Social Determinants of Health and the Health Divide
Jul 17, 2013·Annals of Internal Medicine·Andrea CiprianiGeorgia Salanti
Oct 8, 2013·PloS One·Anna ChaimaniGeorgia Salanti
Feb 4, 2014·The Journal of the American Academy of Orthopaedic Surgeons·Richard L UhlAndrew H Dubin
Mar 26, 2014·Annals of the Rheumatic Diseases·Damian HoyRachelle Buchbinder
Jul 6, 2014·PloS One·Georgia SalantiJulian P T Higgins
Oct 16, 2014·Statistics in Medicine·Dimitris MavridisGeorgia Salanti
Jun 2, 2015·The Journal of Pain : Official Journal of the American Pain Society·Richard L Nahin
Jun 1, 2012·Research Synthesis Methods·Anna Chaimani, Georgia Salanti
Sep 26, 2015·The Cochrane Database of Systematic Reviews·Angela G E M de BoerJos H Verbeek
Oct 23, 2015·International Journal of Occupational Medicine and Environmental Health·Negah Tavakoli-FardMarzieh Nojomi
Dec 10, 2015·Brain Injury : [BI]·Birgit H P M Donker-CoolsMonique H W Frings-Dresen
Jan 13, 2016·Research Synthesis Methods·Orestis EfthimiouUNKNOWN GetReal Methods Review Group
Oct 19, 2016·Pain·Amanda C de C Williams, Kenneth D Craig
Jul 21, 2016·European Archives of Psychiatry and Clinical Neuroscience·Stefan LeuchtGeorgia Salanti
Dec 4, 2016·Internal and Emergency Medicine·Benjamin RouseTianjing Li
Jul 5, 2018·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Crystian B OliveiraBart W Koes
Aug 30, 2019·BMJ : British Medical Journal·Jonathan A C SterneJulian P T Higgins
Mar 20, 2020·Psychiatric Services : a Journal of the American Psychiatric Association·Joseph Marrone, Margaret A Swarbrick

❮ Previous
Next ❯

Citations


❮ Previous
Next ❯

Software Mentioned

Confidence in Network Meta - Analysis ( CINeMA )
Cochrane risk of bias ( RoB
Excel
NMA
EndNote
NOVEL
Stata
CINeMA

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.