Interventions to improve patient understanding of cancer clinical trial participation: a systematic review

European Journal of Cancer Care
C Y KaoB Hamilton

Abstract

Patient misunderstanding of cancer clinical trial participation is identified as a critical issue and researchers have developed and tested a variety of interventions to improve patient understanding. This systematic review identified nine papers published between 2000 and 2013, to evaluate the effects of interventions to improve patient understanding of cancer clinical trial participation. Types of interventions included audio-visual information, revised written information and a communication training workshop. Interventions were conducted alone or in combination with other forms of information provision. The nine papers, all with methodological limitations, reported mixed effects on a small range of outcomes regarding improved patient understanding of cancer clinical trial participation. The methodological limitations included: (1) the intervention development process was poorly described; (2) only a small element of the communication process was addressed; (3) studies lacked evidence regarding what information is essential and critical to enable informed consent; (4) studies lacked reliable and valid outcome measures to show that patients are sufficiently informed to provide consent; and (5) the intervention development pro...Continue Reading

References

Jan 1, 1996·Medical Decision Making : an International Journal of the Society for Medical Decision Making·M Holmes-RovnerG Talarczyk
May 20, 1999·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·C K Daugherty
May 20, 2000·JAMA : the Journal of the American Medical Association·E J EmanuelC Grady
Oct 25, 2000·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·P HietanenP Absetz
Feb 24, 2001·Journal of the National Cancer Institute·S JoffeJ C Weeks
Mar 1, 2003·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Cathy A CoyneUNKNOWN Eastern Cooperative Oncology Group
Oct 7, 2004·JAMA : the Journal of the American Medical Association·James Flory, Ezekiel Emanuel
Dec 21, 2006·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Elizabeth L StrevelLillian L Siu
Dec 30, 2006·Nursing Ethics·Patricia JaspersRinus Wanders
Jun 16, 2007·Journal of Cancer Education : the Official Journal of the American Association for Cancer Education·Ricardo J WrayKaren M Emmons
Sep 1, 2009·American Journal of Surgery·Matthew E FalagasGeorge Peppas
Dec 5, 2009·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Addie C WoottenAnthony J Costello
Mar 25, 2010·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·M JeffordJ Reynolds
Apr 2, 2010·Medical Decision Making : an International Journal of the Society for Medical Decision Making·Yael SchenkerDean Schillinger
Jul 2, 2010·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Richard F BrownMartin Tattersall
Apr 20, 2011·European Journal of Cancer Care·G BeadleP Yates
Nov 20, 2012·International Journal of Nursing Studies·Peter Craig, Mark Petticrew
Nov 20, 2012·International Journal of Nursing Studies·Peter CraigMark Petticrew

❮ Previous
Next ❯

Citations

Dec 19, 2018·Current Opinion in Supportive and Palliative Care·Danique W Bos-van den HoekInge Henselmans
Mar 1, 2017·European Journal of Cancer Care·D Weller
Mar 11, 2017·Science and Engineering Ethics·Henri-Corto StoekléChristian Hervé
May 11, 2017·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Sarah B GarrettDaniel Dohan

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Archives of Pediatrics & Adolescent Medicine
Lawrence S Wissow, Lori Hamby Erby
Journal of Clinical Orthodontics : JCO
V E Mascia, M S Lemchen
© 2022 Meta ULC. All rights reserved