Intestinal Involvement in Kawasaki Disease

The Journal of Pediatrics
Claudia ColombaAntonio Cascio

Abstract

To describe a case of Kawasaki disease with intestinal involvement and to analyze other published reports to define clinical characteristics, diagnostic issues, and therapeutic approaches of gastrointestinal involvement in Kawasaki disease. A computerized search without language restriction was conducted using PubMed and SCOPUS. An article was considered eligible for inclusion in the systematic review if it reported data on patient(s) with intestinal involvement in Kawasaki disease. Our case was also included in the analysis. Thirty-three articles reporting 48 cases of Kawasaki disease with intestinal involvement were considered. Fever, abdominal pain, and vomiting were the most frequent symptoms observed and typical Kawasaki disease signs and symptoms appeared after intestinal complaints in all cases. Plain radiographs, ultrasonography, and computed tomography showed pseudo-obstruction as the most frequent sign of gastrointestinal involvement; 25 patients underwent surgery. Cardiac involvement was documented in 21 cases. All but three patients received medical treatment with immunoglobulin intravenous or aspirin. The outcome was good in 28 patients; 7 patients showed persistence of coronary artery abnormalities; 1 patient deve...Continue Reading

Citations

Feb 7, 2019·Clinical and Experimental Medicine·Yu PengZheng Zou
Aug 29, 2019·Expert Review of Clinical Immunology·Ankur Kumar JindalSurjit Singh
May 28, 2020·Nature Reviews. Rheumatology·Magali Noval Rivas, Moshe Arditi
Jul 29, 2020·Frontiers in Pediatrics·Marco CazzanigaRosa Maria Dellepiane
Apr 25, 2020·Indian Journal of Pediatrics·Pediredla KarunakarBalamurugan Kalyanaprabhakaran
Jul 16, 2020·Pediatric Rheumatology Online Journal·Xiaoliang LiuChuan Wang
Sep 13, 2020·Orphanet Journal of Rare Diseases·Xiaoliang LiuChuan Wang
Oct 3, 2020·The Pediatric Infectious Disease Journal·Yara-Natalie AboGabrielle M Haeusler
Jan 5, 2021·Journal of Clinical Immunology·Julie ToubianaSlimane Allali
Jan 13, 2021·Pediatric Radiology·Edward P Fenlon IiiAlexis B R Maddocks
Jan 13, 2021·The Pediatric Infectious Disease Journal·Hiroshi HayashiHiroshi Hataya
Dec 29, 2020·The Pediatric Infectious Disease Journal·Yara-Natalie AboGabrielle M Haeusler
Apr 21, 2021·Italian Journal of Pediatrics·Alice Annalisa MedagliaClaudia Colomba
May 7, 2021·The Pediatric Infectious Disease Journal·Yara-Natalie AboGabrielle M Haeusler
Aug 10, 2021·Case Reports in Pediatrics·Zohair El HaddarAbdeladim Babakhouya
Apr 5, 2021·Gastroenterology·Kazuki Iio, Hiroshi Sakakibara
Oct 16, 2021·European Journal of Pediatrics·Jinling Hu, Weidong Ren

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