Intestinal transplantation for children with short bowel syndrome

Seminars in Pediatric Surgery
J Reyes

Abstract

Intestinal transplantation has emerged as a feasible alternative in the treatment of children with short gut syndrome. The challenges in the management of these patients include maintaining a tight balance between the degree of immunosuppression necessary to prevent graft-versus-host disease and rejection. At the same time, this amount of immunosuppression is associated with a high risk for lymphoproliferative disorders and intestinal-derived sepsis. Current 3-year patient and graft survival rates are 55% and 50%, respectively. The indications, morbidity, and timing for referral are discussed.

References

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Citations

Jul 16, 2003·Journal of Pediatric Surgery·Anita M NucciEdward M Barksdale
Aug 9, 2005·Seminars in Pediatric Surgery·John K Petty, Moritz M Ziegler
Apr 4, 2006·The Surgical Clinics of North America·John R GoscheSaleem Islam
Mar 3, 2012·Transplant International : Official Journal of the European Society for Organ Transplantation·Tatsuaki TsuruyamaHironori Haga
Feb 1, 2005·World Journal of Gastroenterology : WJG·Shu-Feng WangKun Gao
Aug 15, 2003·World Journal of Gastroenterology : WJG·Shu-Feng Wang, Guo-Wei Li
Mar 17, 2011·Journal of Pediatric Gastroenterology and Nutrition·Ugur HalacOlivier Goulet
May 26, 2009·Journal of Pediatric Gastroenterology and Nutrition·Igor SukhotnikJorge G Mogilner
Jul 11, 2006·World Journal of Gastroenterology : WJG·Da-Xun PiaoYing-Hui Guan

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