Intestinal transplantation: living related

British Medical Bulletin
S G Pollard

Abstract

The use of live donors in intestinal transplantation could potentially both reduce the severity of rejection responses against this highly immunogenic organ by better tissue matching and also reduce cold ischaemia times. These two advantages over cadaveric grafts could preserve mucosal integrity and reduce the risk of systemic sepsis from bacterial translocation. The disadvantages of live donation are the inherent risk to the donor and the compromise of using a shorter graft. Although only a handful of such cases have been performed, the success rate has been high and this is a therapeutic modality which should be explored further.

Citations

Sep 6, 2012·Indian Journal of Gastroenterology : Official Journal of the Indian Society of Gastroenterology·Vinay KumaranSamiran Nundy
Aug 11, 2001·Transplantation Proceedings·A I ShararaM Khalifeh
Oct 7, 2006·Current Opinion in Gastroenterology·K R Prasad, S G Pollard
Oct 20, 2004·Annals of Surgery·Giuliano TestaEnrico Benedetti
Feb 13, 2001·The Journal of Surgical Research·J LauronenT Paavonen
Jun 17, 2003·The British Journal of Surgery·S J MiddletonN V Jamieson
May 24, 2006·World Journal of Gastroenterology : WJG·Sanjay Kulkarni, David-C Cronin

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