Intra-abdominal metastases from soft tissue sarcoma

Journal of Surgical Oncology
Kasim A BehranwalaJ Meirion Thomas

Abstract

To define the clinical features and prognosis of patients with abdominal metastasis from primary soft tissue sarcoma (STS) at other sites. All patients with abdominal metastasis from STS were identified from the Royal Marsden Hospital Sarcoma Unit prospective database from January 1990 to July 2001. Nineteen patients developed abdominal metastasis out of a cohort of 2127 patients (0.9%) evaluated during the study interval. The median age was 49 (19-71) years. The median time to abdominal metastasis from diagnosis of the primary was 27 (8-91) months. The presenting complaints were incomplete intestinal obstruction (n = 5), abdominal pain (n = 4), mass (n = 2), gastrointestinal bleed (n = 2), urinary obstruction (n = 2), anorexia (n = 1), and abdominal distension (n = 1). Emergency laparotomy was done for perforative peritonitis (n = 2), intussusception (n = 2), and bleed in spleen (n = 1). Two patients were asymptomatic. The common histologies were myxoid liposarcoma (n = 6) and leiomyosarcoma (n = 4). The median follow-up of survivors post metastasis was 12 months. Abdominal metastatectomy was performed in 16 patients, 3 of these patients had abdominal recurrences. The 1- and 2-year overall disease specific survival for the 19 ...Continue Reading

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Citations

Oct 25, 2008·World Journal of Surgery·A RehdersX Rogiers
Apr 30, 2013·Surgical Oncology Clinics of North America·Nicole A LarrierBrian E Brigman
Sep 26, 2007·International Journal of Radiation Oncology, Biology, Physics·B Ashleigh GuadagnoloRaphael E Pollock
Jan 30, 2015·Critical Reviews in Oncology/hematology·Timothée OlivierJuliette Thariat
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Aug 15, 2006·Japanese Journal of Clinical Oncology·Fabio CarboniEugenio Santoro
Mar 7, 2020·World Journal of Clinical Oncology·Maria Anna SmolleGerwin Alexander Bernhardt

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