Intra-arterial chemotherapy for head and neck cancer: experiences from three continents

Surgical Oncology Clinics of North America
K Thomas Robbins, Akihiro Homma

Abstract

Intra-arterial infusion of chemotherapy agents for cancer of the head and neck has been used for several decades. This article provides the rationale, historical background, and current state of investigations for patients treated in this manner. The experience with this route of drug delivery comes from three geographic regions: Europe, Japan, and North America. While the results of the trials have yet to establish the approach as being superior to intravenous infusions, continued research is warranted.

References

Apr 1, 1989·Archives of Otolaryngology--head & Neck Surgery·Y Y LeeH Goepfert
Oct 18, 1989·Journal of the National Cancer Institute·R GoelS B Howell
Mar 16, 1988·Journal of the National Cancer Institute·R L Dedrick
Dec 1, 1982·Annals of Internal Medicine·S B HowellM Green
Jun 7, 2007·American Journal of Clinical Oncology·Anna RabbaniWilliam M Mendenhall

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Citations

Oct 22, 2015·Japanese Journal of Clinical Oncology·Akihiro HommaMasato Fujii
Apr 10, 2018·Frontiers in Oncology·Teruki YanagiHiroo Hata

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