Intra-epidermal carcinoma of the eyelid margin.

The British Journal of Dermatology
D I McCallumM A Wroughton

Abstract

Twenty-two cases of intra-epidermal carcinoma of the ciliary margin have been diagnosed in a 15-year survey. The clinical appearance is variable, resembling in some instances a benign warty lesion, and in others a fully developed squamous cell carcinoma. As the lesion grows it produces keratotic plugging of the lash follicles and nodules on the lid margin; in due course this results in loss of the related cilia. When dermal invasion occurs the resultant squamous cell carcinoma is potentially dangerous because of the involvement of the adnexal structures, which on the ciliary margins are particularly large and penetrate deeply into the lid substance. Adequate biopsy which includes at least one lash follicle is essential for accurate diagnosis, and treatment requires complete excision with a reasonable margin for safety. Of the twenty-two patients, nineteen were male and three female; fourteen of the men involved had handled oils and greases for prolonged periods.

References

Jan 1, 1962·British Journal of Plastic Surgery·J SHULMAN
Jul 5, 2007·Journal of Lipid Research·Barbara P AtshavesFriedhelm Schroeder

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Citations

Mar 12, 2002·Clinical & Experimental Ophthalmology·Timothy J SullivanKevin J Whitehead
Jun 1, 1977·International Journal of Dermatology·D M StevensR S Bart
Mar 17, 2007·Clinical & Experimental Ophthalmology·Vanessa LimawararutDinesh Selva
Oct 7, 2004·Ophthalmology·Raman MalhotraShyamala C Huilgol
Aug 4, 2006·Journal français d'ophtalmologie·L Thomas, S Dalle

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