Intra-synovial, compared to intra-articular morphine provides better pain relief following knee arthroscopy menisectomy

Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie
Mordechai KligmanMoshe Roffman

Abstract

To evaluate the analgesic effect of morphine 1 mg administered into the synovial tissue and the outer third of the meniscus after knee arthroscopy. In a prospective, double-blind, randomized study, 60 patients who required elective knee arthroscopy were assigned to two groups: Group A consisted of 30 patients who received a direct injection of morphine 1 mg into either the synovial tissue or the outer third of the meniscus following menisectomy. Group B consisted of 30 patients who received a direct injection of NaCl 0.9% 1 mL into the synovial tissue or the outer third of the meniscus following menisectomy. At the end of the operation Group A received an intra-articular injection of NaCl 0.9% 1 mL and bupivacaine 0.5% 10 mL and Group B received an intra-articular injection of morphine 1 mg and bupivacaine 0.5% 10 mL. Analgesic effect was evaluated by pain intensity (visual analogue scale; VAS) and analgesic requirements (paracetamol) during the first one, three, six, 12, 24, and 48 hr postoperatively. There was no significant difference between the two groups within the first six hours and after 24 hr following the operation regarding VAS score and analgesic requirements. At 12 and 24 hr following the operation, the VAS score ...Continue Reading

References

Jan 1, 1992·European Journal of Clinical Pharmacology·A J LawrenceD C Moriarty
Feb 1, 1994·Arthroscopy : the Journal of Arthroscopic & Related Surgery : Official Publication of the Arthroscopy Association of North America and the International Arthroscopy Association·B P BodenR A Moyer
Jan 1, 1993·Anesthesia and Analgesia·C Stein
May 1, 1996·Anesthesia and Analgesia·S S Reuben, N R Connelly
Oct 31, 1997·Arthroscopy : the Journal of Arthroscopic & Related Surgery : Official Publication of the Arthroscopy Association of North America and the International Arthroscopy Association·M D RichardsonK McCullough
Dec 29, 2000·The Journal of Bone and Joint Surgery. American Volume·S S Reuben, J Sklar

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Citations

Dec 31, 2004·Current Pain and Headache Reports·Jochen Oeltjenbruns, Michael Schäfer
Oct 6, 2006·Current Opinion in Anaesthesiology·Diane L DeHaven-Hudkins

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