Intra-tester and inter-tester reliability of post-occlusive reactive hyperaemia measurement at the hallux

Microvascular Research
Alex BarwickVivienne Helaine Chuter

Abstract

Post-occlusive reactive hyperaemia (PORH) is a measurement of the vasodilatory capacity of the microvasculature that is associated with cardiovascular disease, peripheral arterial disease and foot ulceration. The reliability of its measurement in the hallux (great toe) for clinical and research purposes has not been adequately assessed. This study assesses both the intra-tester reliability and inter-tester reliability of four methods of assessing PORH in the hallux. A within-subject repeated measures design was used. Forty-two participants underwent PORH testing using four methods: pressure measurement with photoplethysmography; an automated laser Doppler technique with local heating; an automated laser Doppler technique without local heating; and a manual laser Doppler technique. Participants underwent testing on two occasions with a three to 14 day interval. Laser Doppler measurement with a heating probe was found to be the most reliable method of PORH measurement. The index of the area under the curve pre- and post-occlusion and peak perfusion as a percentage of baseline were the most reliable variables. PORH can be reliably measured using laser Doppler when combined with a heating probe. Further research is required to dete...Continue Reading

References

Feb 1, 1991·Journal of the American Podiatric Medical Association·A F HoffmanM J Matthews
Sep 13, 2001·Diabetic Medicine : a Journal of the British Diabetic Association·B BrooksD K Yue
Jul 1, 1953·Circulation·M D PAREIRAH T BLUMENTHAL
Jul 6, 2004·Journal of Pharmacological and Toxicological Methods·Get Bee Yvonne TeeAbdul Rashid Abdul Rahman
Aug 30, 2005·Journal of Pharmacological and Toxicological Methods·Get Bee Yvonne-TeeAbdul Rashid Abdul Rahman
Aug 1, 2006·Trends in Pharmacological Sciences·Jean-Luc CracowskiJohn R Halliwill
Jul 23, 2009·Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)·Sara BergstrandMargareta Lindgren
Aug 15, 2009·Diabetes/metabolism Research and Reviews·Clare Y L Chao, Gladys L Y Cheing
Aug 4, 2010·Autoimmunity Reviews·S SitiaM Turiel
Feb 9, 2012·Nature Reviews. Nephrology·David A LongLeon G Fine
Dec 3, 2014·Microvascular Research·Eduardo TibiricaGlaucia M M Oliveira

❮ Previous
Next ❯

Citations

May 9, 2016·Journal of Diabetes and Its Complications·Alex L BarwickVivienne H Chuter
Aug 2, 2016·Journal of Science and Medicine in Sport·Sean M LantingVivienne H Chuter
Jun 13, 2020·Frontiers in Endocrinology·Gayathri BalasubramanianRoozbeh Naemi
Mar 4, 2021·Microcirculation : the Official Journal of the Microcirculatory Society, Inc·Gayathri BalasubramanianRoozbeh Naemi

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiovascular Disease Pathophysiology

Cardiovascular disease involves several different processes that contribute to the pathological mechanism, including hyperglycemia, inflammation, atherosclerosis, hypertension and more. Vasculature stability plays a critical role in the development of the disease. Discover the latest research on cardiovascular disease pathophysiology here.