PMID: 9436561Jan 22, 1998Paper

Intraaortic balloon counterpulsation improves right ventricular failure resulting from pressure overload

The Annals of Thoracic Surgery
W C DarrahA Neal

Abstract

Right ventricular (RV) dysfunction is common after heart transplantation, and myocardial ischemia is considered to be a significant contributor. We studied whether intraaortic balloon counterpulsation would improve cardiac function using a model of acute RV pressure overload. In 10 anesthetized sheep, RV failure was induced using a pulmonary artery constrictor. Baseline measurements included mean systemic blood pressure, RV peak systolic pressure, cardiac index, and RV ejection fraction. Myocardial and organ perfusion were measured using radioactive microspheres. After pulmonary artery constriction, there was an increase in RV peak systolic pressure (32 +/- 2 to 60 +/- 3 mm Hg; p < 0.01) and a decrease in mean systemic blood pressure (68 +/- 4 to 49 +/- 2 mm Hg; p < 0.01), RV ejection fraction (0.51 +/- 0.04 to 0.16 +/- 0.02; p < 0.01), and cardiac index (2.48 +/- 0.04 to 1.02 +/- 0.11; p < 0.01). Blood flow to the RV did not change significantly, but there was a significant reduction in blood flow to the left ventricle. The initiation of intraaortic balloon counterpulsation (1:1) using a 40-mL intraaortic balloon inserted through the left femoral artery resulted in an increase in mean systemic blood pressure (49 +/- 2 to 61 +/...Continue Reading

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Citations

Sep 23, 2010·Critical Care : the Official Journal of the Critical Care Forum·Laura C PriceStephen J Brett
Jul 29, 2011·Heart Failure Reviews·Maya Guglin, Sameer Verma
Sep 27, 2012·Progress in Cardiovascular Diseases·Hooman D Poor, Corey E Ventetuolo
Aug 1, 2015·The Annals of Thoracic Surgery·Akiko TanakaValluvan Jeevanandam
Jul 6, 2015·International Journal of Cardiology·Frederic Vanden EyndenThierry Bove
Nov 28, 2000·The Annals of Thoracic Surgery·O E ArafaJ L Svennevig
Jul 15, 2015·Heart & Lung : the Journal of Critical Care·Carl Johan MalmGöran Dellgren
May 20, 2015·International Journal of Cardiology·Argyrios NtalianisJohn N Nanas
Feb 15, 2014·International Journal of Cardiology·Chris J KapeliosJohn N Nanas
Jul 13, 2011·Journal of Intensive Care Medicine·Ramford Ng, Yerem Yeghiazarians
May 28, 2016·European Heart Journal. Acute Cardiovascular Care·Arun KrishnamoorthyManesh R Patel
Aug 30, 2006·European Journal of Anaesthesiology·K Valchanov, A Vuylsteke
Feb 23, 2018·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Adam D DeVoreAdrian F Hernandez
Jan 24, 2006·American Journal of Physiology. Heart and Circulatory Physiology·Carol A Gibbons KroekerJohn V Tyberg
Oct 22, 2009·The International Journal of Artificial Organs·Jef H GeensBart P Meyns

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