Intraarticular corticosteroid for treatment of osteoarthritis of the knee

The Cochrane Database of Systematic Reviews
N BellamyG Wells

Abstract

Osteoarthritis (OA) is a common joint disorder. In the knee, injections of corticosteroids into the joint (intraarticular (IA)) may relieve inflammation, and reduce pain and disability. To evaluate the efficacy and safety of IA corticosteroids in treatment of OA of the knee. We searched the Cochrane Central Register of Controlled Trials (CENTRAL) (Issue 2, 2003), MEDLINE (to January (week 1) 2006 for update), EMBASE, PREMEDLINE (all to July 2003), and Current Contents (Sept 2000). Specialised journals, trial reference lists and review articles were handsearched. Randomised controlled trials of IA corticosteroids for patients with OA of the knee: single/double blind, placebo-based/comparative studies, reporting at least one core OMERACT III outcome measure. Methodological quality of trials was assessed, and data were extracted in duplicate. Fixed effect and random effects models, giving weighted mean differences (WMD), were used for continuous variables. Dichotomous outcomes were analysed by relative risk (RR). Twenty-eight trials (1973 participants) comparing IA corticosteroid against placebo, against IA hyaluronan/hylan (HA products), against joint lavage, and against other IA corticosteroids, were included.IA corticosteroid w...Continue Reading

Citations

Jan 12, 2007·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Fouad FayadMichel Revel
Oct 27, 2012·Clinical Orthopaedics and Related Research·Gustavo Constantino de CamposOlavo Pires Camargo
Feb 1, 2010·Therapeutic Advances in Musculoskeletal Disease·Ananthila Anandacoomarasamy, Lyn March
Dec 1, 2010·Therapeutic Advances in Musculoskeletal Disease·Claire Y J Wenham, Philip G Conaghan
Jan 22, 2013·BMC Medicine·Paul M Sutton, Edward S Holloway
Apr 14, 2012·Clinical Interventions in Aging·David J BerkoffJon E Block
Jan 5, 2011·Journal of Pain Research·Victor M Goldberg, Laura Goldberg
Feb 6, 2010·The British Journal of General Practice : the Journal of the Royal College of General Practitioners·Nefyn H WilliamsClare Wilkinson
Sep 22, 2015·Langmuir : the ACS Journal of Surfaces and Colloids·Felicitas SchwörerRoland Steitz
Aug 16, 2016·Apoptosis : an International Journal on Programmed Cell Death·Hai-Bin ZhangZhao-Jun Wang
Dec 22, 2016·International Journal of Molecular Sciences·Edith CharlierDominique De Seny
Nov 10, 2017·Singapore Medical Journal·Yiyang LiowVictor Weng Keong Loh
May 2, 2013·The Cochrane Database of Systematic Reviews·Mihir D WechalekarRachelle Buchbinder
Dec 10, 2015·Drugs & Aging·Féline P B KroonMargreet Kloppenburg
Oct 23, 2015·The Cochrane Database of Systematic Reviews·Peter JüniBruno R da Costa
Jul 3, 2015·The Journal of Rheumatology·Andrea Barranjard Vannucci LomonteCristiano Augusto de Freitas Zerbini
Jan 1, 2013·F1000Research·Jasvinder A Singh
Mar 1, 2009·PM & R : the Journal of Injury, Function, and Rehabilitation·Stuart WillickJonathan T Finnoff
May 1, 2010·PM & R : the Journal of Injury, Function, and Rehabilitation·Andrea J BoonJasvinder A Singh
Sep 18, 2007·Archives of Orthopaedic and Trauma Surgery·Michel P J van den BekeromMichiel Mulier
Jul 5, 2007·The Journal of Small Animal Practice·R A PettittM J Guilliard
Aug 1, 2012·Nature Reviews. Rheumatology·Kim BennellBill Vicenzino
Jan 5, 2008·Current Pain and Headache Reports·Carla R ScanzelloAllan Gibofsky
Mar 4, 2008·The Journal of Bone and Joint Surgery. British Volume·S E GwilymA J Carr
May 7, 2008·Current Rheumatology Reports·Carla R ScanzelloAllan Gibofsky
Nov 1, 2011·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·Elizaveta KonStefano Della Villa
May 25, 2012·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·Federico CabitzaPietro Randelli

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.