Intracameral cefazolin as prophylaxis against endophthalmitis in cataract surgery

Journal of Cataract and Refractive Surgery
Pedro RomeroMatias Almena

Abstract

To evaluate the efficacy of prophylactic intracameral cefazolin in preventing endophthalmitis in cataract surgery. Service of Ophthalmology, St. Joan Hospital, Reus, Spain. In this noncontrolled retrospective observational study, all patients had uncombined cataract surgery from January 2001 to December 2004. All cases of postoperative endophthalmitis were related. The patients were classified into 2 groups. The first (n = 3650) had surgery between January 2001 and December 2002, and the second (n = 3618) had surgery between January 2003 and December 2004; the second group received a bolus of intracameral cefazolin instilled at the end of surgery. The rate of postoperative endophthalmitis was lower in the cases with intracameral injection at the end of surgery (0.055%) than in those without cefazolin injection (0.63%). No patients in the group with intracameral cefazoline developed corneal endothelium or retinal toxicity. Intracameral bolus injection of cefazolin (1 mg in 0.1 mL solution) in cataract surgery demonstrated prophylactic efficacy in diminishing the rate of postoperative endophthalmitis without toxic effects on the cornea or retina.

References

Apr 1, 1977·The British Journal of Ophthalmology·G A PeymanD R May
Jan 1, 1989·Ophthalmic Research·G PetroutsosY Pouliquen
Apr 1, 1980·American Journal of Ophthalmology·J H Saunders, S D McPherson
Jan 15, 1994·American Journal of Ophthalmology·S von GuntenP M Leuenberger
Mar 1, 1996·American Journal of Ophthalmology·W A Townsend-PicoJ A Costin
Dec 23, 1998·Survey of Ophthalmology·M S KresloffM A Zarbin
Oct 16, 1999·Ophthalmology·S SchmitzN Pfeiffer
Jan 5, 2002·Ophthalmology·Thomas A CiullaSamuel Masket
Jan 30, 2002·The British Journal of Ophthalmology·Andrew F RileyCharles N McGhee
May 31, 2002·Journal of Cataract and Refractive Surgery·Per G MontanMargareta Rylander
May 31, 2002·Journal of Cataract and Refractive Surgery·Per G MontanCharlotta Zetterström
Jul 13, 2002·European Journal of Ophthalmology·J ErnestP Nemec
Mar 31, 2004·Ophthalmology·Tien Yin Wong, Soon-Phaik Chee

❮ Previous
Next ❯

Citations

Aug 29, 2012·Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics·Regis P KowalskiFrancis S Mah
Mar 7, 2013·Surgical Infections·Dale W BratzlerUNKNOWN Society for Healthcare Epidemiology of America (SHEA)
Mar 12, 2011·The Journal of Antimicrobial Chemotherapy·S M McHughH Humphreys
Dec 20, 2007·Current Opinion in Ophthalmology·Francis Char DeCroos, Natalie A Afshari
Dec 1, 2012·Current Opinion in Ophthalmology·Bradley L Shoss, Linda M Tsai
Dec 31, 2010·Clinical Ophthalmology·Philip T H LamVincent Y W Lee
Oct 31, 2012·Clinical Ophthalmology·Pedro Romero-ArocaFrancisca Bassaganyas
Aug 20, 2008·Indian Journal of Ophthalmology·Aditya KelkarAarofil Shaikh
Dec 9, 2014·Jundishapur Journal of Microbiology·Mahamoudreza PanahibazazEffat Abbasi Montazeri
Mar 13, 2014·Epidemiology and Infection·M A AsencioF Gonzalez-Del Valle
Dec 4, 2014·Journal of Cataract and Refractive Surgery·Rosa Braga-MeleUNKNOWN ASCRS Clinical Cataract Committee
Dec 19, 2015·Ocular Immunology and Inflammation·Ama SadakaMichael S Gilmore
Jul 21, 2012·Journal of Cataract and Refractive Surgery·Germain BarreauPierre-Yves Robert
Nov 24, 2011·Journal of Cataract and Refractive Surgery·Steve A Arshinoff, Paul A Bastianelli
Jul 26, 2011·Journal of Cataract and Refractive Surgery·Mark PackerUNKNOWN ASCRS Cataract Clinical Committee
Feb 16, 2010·Journal of Cataract and Refractive Surgery·David LockingtonDavid Yorston
Aug 19, 2009·Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy·Shinichiro KobayakawaTetsuo Tochikubo
Mar 6, 2016·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Colin S H TanVernon S Chow
Mar 24, 2009·Journal of Cataract and Refractive Surgery·Magela GaratLuis Alvarez-Rubio
Aug 15, 2008·Clinical & Experimental Ophthalmology·Su-Young KimYoung-Chun Lee
Aug 28, 2010·Clinical & Experimental Ophthalmology·Mamie HuiDennis S C Lam
Apr 12, 2016·Journal of Cataract and Refractive Surgery·Louis W Lim, Colin S Tan
Mar 18, 2015·Acta Ophthalmologica·Line KesselJesper Hjortdal
Nov 11, 2014·Clinical & Experimental Ophthalmology·Colin Sh TanLouis W Lim
Jan 29, 2014·Ophthalmic Epidemiology·Maria Angeles AsencioFernando Gonzalez-del Valle
Jun 8, 2015·Journal of Cataract and Refractive Surgery·Colin S H TanKai Xiong Cheong
Dec 3, 2014·Journal of Cataract and Refractive Surgery·Colin S H TanHan Bor Fam
Apr 4, 2015·Journal of Cataract and Refractive Surgery·Colin S H TanKai Xiong Cheong
Aug 7, 2017·Asia-Pacific Journal of Ophthalmology·Aravind HaripriyaDavid F Chang
Mar 1, 2012·Asia-Pacific Journal of Ophthalmology·Philip T H LamDennis S C Lam
Jan 1, 2012·Asia-Pacific Journal of Ophthalmology·Avinash PathengayHarry W Flynn
Mar 30, 2018·AORN Journal·Esther M Johnstone
Dec 23, 2016·Journal of Cataract and Refractive Surgery·Steve A Arshinoff, Milad Modabber
Jul 25, 2017·Journal of Cataract and Refractive Surgery·Peter E Libre, Sean Mathews
Jul 5, 2011·European Journal of Ophthalmology·Angelo BalestrazziMario Fruschelli
May 14, 2017·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Louis W Lim, Colin S Tan
Jan 31, 2021·Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie·Mark K LukewichSteve A Arshinoff
Jan 19, 2013·American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists·Dale W BratzlerUNKNOWN Society for Healthcare Epidemiology of America

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.