Intracanal Cryotherapy Reduces Postoperative Pain in Teeth with Symptomatic Apical Periodontitis: A Randomized Multicenter Clinical Trial

Journal of Endodontics
Jorge VeraAna Arias

Abstract

A prospective, multicentered, randomized clinical trial was designed to assess if controlled irrigation with cold saline could result in less incidence and intensity of postoperative pain in patients presenting with pulp necrosis and symptomatic apical periodontitis. A total of 210 patients (presenting with necrotic uniradicular teeth with a diagnosis of symptomatic apical periodontitis and a preoperative visual analog scale (VAS) score higher than 7) were randomly allocated in the control or experimental group after the completion of shaping and cleaning procedures. The experimental group received a final irrigation with 20 mL sterile cold (2.5°C) saline solution delivered to the working length with a sterile, cold (2.5°C) Endovac microcannula (Kerr Endo, Orange Country, CA) for 5 minutes. The same protocol was used in the control group with room temperature saline solution. Patients were instructed to record the presence, duration and level of postoperative pain, and analgesic medication intake. A logistic regression was used to compare the incidence of postoperative pain and the need for painkillers between groups. Differences in general pain intensity between groups were analyzed using the ordinal (linear) chi-square test. ...Continue Reading

Citations

Jan 10, 2019·Acta Odontologica Scandinavica·Cangül KeskinDuygu H Güler
Mar 8, 2019·Statistical Methods in Medical Research·Tong-Yu LuSiu Hung Cheung
Apr 9, 2020·International Endodontic Journal·V NagendrababuP M H Dummer
Nov 23, 2020·Clinical Oral Investigations·Laise Pena Braga MonteiroJuliana Melo da Silva Brandão
Feb 16, 2021·Journal of Dental Anesthesia and Pain Medicine·Alpa GuptaNishant Chauhan
Mar 8, 2020·Canadian Journal of Pain = Revue Canadienne De La Douleur·Hance A ClarkeRobin S McLeod
May 26, 2021·Photodiagnosis and Photodynamic Therapy·Larissa Vilas-BoasMarcelo Santos Coelho

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