PMID: 38715May 1, 1979

Intracecal endotoxin and lactate during the onset of equine laminitis: a preliminary report

American Journal of Veterinary Research
J N MooreR F Sprouse

Abstract

Cecal fluid from two adult horses was assayed by the limulus amebocyte lysate system for endotoxin before and after carbohydrate overload of the gastrointestinal tract. There were increases in cecal fluid endotoxin concentrations at the 3-, 6-, and 12-hour samplings when compared with base-line values. Concomitant cecal fluid lactate concentrations and pH values increased and decreased, respectively. Both horses subsequently developed clinical signs of acute laminitis.

Related Concepts

Cecum
Endotoxins
Foot Diseases
Hoof
Horse Diseases
Hydrogen-Ion Concentration
Lactates
Limulus Test

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