PMID: 42909Nov 1, 1979

Intracellular dye-marked enkephalin neurons in the magnocellular preoptic nucleus of the goldfish hypothalamus

Proceedings of the National Academy of Sciences of the United States of America
T A Reaves, J N Hayward

Abstract

A method that combines intracellular recording, dye marking, and immunocytochemistry makes the study of functional and morphological aspects of enkephalin neurons in the magnocellular preoptic nucleus of the goldfish hypothalamus feasible. By use of multiple techniques, enkephalin neurons can be distinguished from other brain cells and can be reconstructed from drawings of serial sections containing the dye-injected opioid cells. These enkephalin cells and their processes measure 14-42 micron in somata diameter and are unipolar, bipolar, or multipolar. Their electrophysiological properties match those of other mammalian and fish magnocellular endocrine cells. This report confirms the one neuron-one hormone (peptide) hypothesis, supports synaptic over electronic coupling between enkephalin and adjacent hypothalamic neurons, and suggests that chemical and functional classification of single electrophysiologically and neuroanatomically studied central neurons can be achieved.

References

Aug 1, 1988·Journal of Neuroscience Methods·K Horikawa, William E Armstrong
Jul 1, 1994·Journal of Neuroscience Methods·R Wegerhoff, O Breidbach
Sep 25, 1981·Neuroscience Letters·T A Reaves, J N Hayward
Mar 1, 1982·The Journal of Clinical Investigation·S Ishikawa, R W Schrier
Jul 6, 2015·International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience·Saikat P BiswasDharmendra P Sinh
Jan 1, 1983·Neuropeptides·M Coletti-PrevieroR Zwilling
Dec 7, 2018·Journal of Neuroendocrinology·William E ArmstrongCelia D Sladek

Citations

Mar 18, 1977·Brain Research·R Simantov, S H Snyder
Nov 1, 1978·The Journal of Comparative Neurology·M SarP Cuatrecasas
Mar 1, 1978·British Journal of Pharmacology·G W BissetW Feldberg
Mar 14, 1975·Brain Research·K T Brown, D G Flaming
Mar 1, 1964·The Journal of General Physiology·E R KANDEL

Related Concepts

Endorphins
Protoplasm
Resting Potentials
Neurons
Preoptic Areas
Organum Vasculosum Laminae Terminalis
Hypothalamo-Hypophyseal System
Basal Nucleus of Meynert
Immunocytochemistry
Neurohormones

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