PMID: 7536643Jan 14, 1995Paper

Intracellular injections of lucifer yellow into lightly fixed mitral cells reveal neuronal dye-coupling in the developing rat olfactory bulb

Brain Research. Developmental Brain Research
M A PaternostroP C Brunjes

Abstract

We report that intracellular injections of Lucifer Yellow into lightly fixed mitral cells revealed dye-coupling between mitral cells and between mitral and granule cells in the form of discrete, radially oriented cell clusters. Dye-coupling was observed in animals as early as postnatal day 10 (P10) and at least until P30. In P10 rats, a mean of 2.5 dye-coupled mitral cells and 27 granule cells were observed per column. Mean column depth and width were 169 microns and 86 microns respectively. Most of the dye-filled granule cells were found within 150 microns of the mitral cell layer. No significant changes were found at P20. By P30, the mean number of granule cells per column increased to 42 and the addition of granule cells occurred in areas proximal to the mitral cell layer. Immunocytochemical results indicate that the developing bulb contains a large concentration of the gap junction protein Connexin 43 (Cx43). Cx43-like immunoreactivity was found at all ages examined, with the most intense staining in the nerve and glomerular layers. Less intense Cx43-like immunoreactivity was found in both the mitral and granule cell layers, with Cx43-like immunoreactive puncta observed between and around cell body profiles. Freeze-fracture...Continue Reading

References

Jun 15, 1979·The Journal of Comparative Neurology·W B StewartG M Shepherd
Sep 1, 1976·The Journal of Comparative Neurology·J W Hinds, P L Hinds
Nov 15, 1992·The Journal of Comparative Neurology·F MiragallR Dermietzel
Sep 1, 1992·Journal of Neuroscience Methods·L A Coleman, M J Friedlander
Jul 31, 1992·Science·R YusteL C Katz
Apr 1, 1991·Neuroscience Letters·A MatsumotoS Hyodo
Mar 1, 1991·Neuron·M V BennettJ C Sáez
Mar 1, 1991·The Journal of Comparative Neurology·P E Micevych, L Abelson
May 1, 1991·The Journal of Comparative Neurology·N BuonvisoJ W Scott
Oct 1, 1991·The Journal of Steroid Biochemistry and Molecular Biology·J W Scott
Apr 6, 1990·Neuroscience Letters·C C NausJ F Bechberger
Mar 15, 1986·Experientia·J W Scott
Dec 3, 1986·Neuroscience Letters·J H Rho, R L Sidman
Dec 1, 1989·Proceedings of the National Academy of Sciences of the United States of America·R DermietzelK Willecke
Mar 15, 1988·The Journal of Comparative Neurology·L L Frazier, P C Brunjes
Sep 1, 1985·The Journal of Comparative Neurology·M S KaplanJ W Hinds
Jan 1, 1983·Experimental Brain Research·S A Bayer
Nov 12, 1993·Science·S R RobinsonD I Vaney
Jan 1, 1994·Brain Research. Brain Research Reviews·P C Brunjes
Jan 1, 1993·Cell·S H DeVries, D A Baylor
Feb 1, 1993·Microscopy Research and Technique·J W ScottN Buonviso
Feb 1, 1993·Microscopy Research and Technique·J S Kauer, A R Cinelli
Apr 15, 1993·Proceedings of the National Academy of Sciences of the United States of America·K M GuthrieC Gall

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Citations

Jun 1, 1996·Molecular Neurobiology·B Rörig, B Sutor
Jan 14, 1998·Brain Research. Developmental Brain Research·J H HaringK M Faber
Jun 15, 1999·Brain Research. Developmental Brain Research·N D AbergP S Eriksson
Feb 26, 2004·Neuron·Michael V L Bennett, R Suzanne Zukin
Feb 12, 1999·Brain Research. Brain Research Protocols·G Prusky, T Arjannikova
Jan 1, 1997·The European Journal of Neuroscience·R Bruzzone, C Ressot
Mar 22, 2007·Acta Histochemica Et Cytochemica·Norio Iijima, Takahiko Yokoyama
Oct 7, 2003·The Journal of Comparative Neurology·Karen J BlinderAsaf Keller
Jul 31, 2003·The European Journal of Neuroscience·Martin TheisKlaus Willecke
Nov 28, 2002·The Journal of Comparative Neurology·Kathleen M Guthrie, Christine Gall
Sep 12, 2000·The Journal of Comparative Neurology·C ZhangD Restrepo
May 7, 2002·Journal of Neuroscience Research·J DuK A Hamilton
May 29, 2000·Journal of Cellular Physiology·O V KolomytkinJ A Albright
Jul 24, 2004·The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry·Pierre-Marie LledoMorgane Lemasson
Dec 25, 2004·Physiological Reviews·Pierre-Marie LledoJean-Didier Vincent
Oct 16, 2002·Nature Neuroscience·Nathan E Schoppa, Gary L Westbrook
May 13, 2003·Journal of Neurophysiology·Daniel Friedman, Ben W Strowbridge
Jan 11, 2002·Developmental Biology·L K Cole, L S Ross
Mar 23, 2004·Biochimica Et Biophysica Acta·Sheriar G HormuzdiRoberto Bruzzone
Jun 1, 2005·Neuron·Jason M ChristieGary L Westbrook

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