Intracellularly injected cobaltous ions accumulate at synaptic densities

Science
C E Phillips

Abstract

Physiologically identified neurons in the locust were iontophoretically injected with a mixture of cobaltous and potassium ions. After being fixed for electron microscopy, 2.5-micrometer sections of the epoxy-embedded ganglia were intensified with silver. The intensified material was resectioned and examined in the electron microscope. The cobalt-silver precipitate appeared as discrete densities. Localized accumulations of the precipitate were seen within the injected cell along the neuronal membranes and especially at synapses. Location and recognition of the stained neuron in the electron microscope was facilitated by the tendency of the cobaltous ions to aggregate at the synaptic sites.

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Citations

Jan 1, 1988·Archives of Dermatological Research·J SalogaG Kolde
Jan 1, 1982·Journal of Neuroscience Methods·S L SenftD L Alkon
Jan 1, 1983·Progress in Neurobiology·J A Wilson, C E Phillips
Aug 1, 1981·Environmental Health Perspectives·K W Jennette
Sep 1, 1983·Journal of Neurobiology·J A WilsonB Müller
Sep 15, 2004·Marine Environmental Research·M CheggourS Benbrahim
Sep 1, 1982·Journal of Neurobiology·C M Hackney, J S Altman
Sep 1, 1982·Journal of Neurobiology·J A WilsonF Huber
Apr 1, 1986·The Journal of Comparative Neurology·G HoyleC Phillips
Apr 1, 1986·The Journal of Comparative Neurology·G Hoyle
Dec 28, 1981·Brain Research·M E Adams, M O'Shea
May 1, 1981·Journal of Neurobiology·C E Phillips
Jun 22, 1984·Science·R K Murphey, C A Lemere

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