Intracerebral schwannoma presenting as classic temporal lobe epilepsy

Journal of Neurosurgery
Daipayan GuhaTaufik A Valiante

Abstract

Schwannomas of the brain parenchyma are extremely rare, occurring mostly in children and young adults. Fewer than 50 cases have been reported in the English-language literature. Isolated temporal lobe epilepsy is a rare presentation of intracerebral schwannomas, with only 2 reported cases. The authors present the case of a 51-year-old woman with a 4-year history of medication-refractory seizures, which were localized on electroencephalography to the right temporal lobe. Magnetic resonance imaging identified a mildly space-occupying, T2 hyperintense, and inhomogeneously enhancing mass in her left mesial temporal lobe. Histological, immunohistochemical, and electron microscopy examinations of the surgical specimen established a diagnosis of intracerebral schwannoma. Accurate diagnosis of intracerebral schwannomas is essential, particularly in younger patients, given the lesions' nature, amenity to resection, favorable long-term prognosis, and broad radiological differential. The etiology of these lesions remains unknown, and multiple proposed theories are reviewed.

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Citations

Jul 25, 2013·British Journal of Neurosurgery·Jose Luis SanmillánJuan José Acebes
Jan 18, 2017·World Neurosurgery·Marcos Devanir Silva da CostaManoel Antonio Paiva Neto
Sep 21, 2018·The International Journal of Neuroscience·Hirotomo TenAkio Morita
Oct 14, 2017·Surgical Neurology International·Uday S RaswanAltaf Umar Ramzan
Dec 3, 2013·Journal of Korean Neurosurgical Society·Sungjoon LeeChun Kee Chung
Dec 2, 2019·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Beste GulsunaEmrah Celtikci
Jul 18, 2018·Oncology Letters·Yufei GaoXingyi Jin
Nov 14, 2013·The Journal of Craniofacial Surgery·Li MaYi-Rong Wang
Apr 22, 2017·Case Reports in Pathology·Lauren PearsonMaryam Zenali
Jun 18, 2020·Surgical Neurology International·Daisuke WajimaTaiji Yonezawa
Oct 22, 2020·Journal of Neurological Surgery. Part A, Central European Neurosurgery·Alexey TokarevElizabeth Rozhnova

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Methods Mentioned

BETA
Electron
biopsy
electron microscopy

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