Abstract
Adult cats were subjected to subarachnoid hemorrhage by three repeated intracisternal injections of autogenous nonheparinized blood (2 ml/injection) at weekly intervals. Histological studies (light and electron microscope) were made of the basilar artery and the middle cerebral arteries of all animals. In the subarachnoid-injected hemorrhaged animals, a large, organized blood clot extended uninterrupted along the lateral and ventral aspect of the medulla and pons, covering or partially encircling the basilar artery for most of its course. Smaller and less organized clots extended into various mesencephalic regions. Histologic findings in vessels from the injected hemorrhaged group were similar to those of control animals, showing neither evidence of endothelial damage, intimal proliferation, nor other significant vascular changes. The results suggest that the injection of blood into the subarachnoid space does not produce significant structural changes, but that the primary stimulus for the initiation of such pathologic events is closely tied to vessel rupture.
References
Mar 1, 1976·Neurologia Medico-chirurgica·H KinY Yoshida
Jan 1, 1979·Neurologia Medico-chirurgica·K SomedaH Matsumura
Jan 1, 1978·Journal of Neurosurgery·M R MaybergT M Sundt
Feb 1, 1978·Journal of Neurosurgery·E TaniY Ito
Apr 1, 1978·Journal of Neurosurgery·J T Hughes, P M Schianchi
Jan 1, 1976·Acta neurochirurgica·M MizukamiY Yoshida
Feb 1, 1985·Neurosurgery·R R SmithJ M Cruse
Apr 1, 1985·Journal of Neurosurgery·J P KappR R Smith
Dec 1, 1985·Surgical Neurology·J I AusmanC S Son
Jul 1, 1974·Journal of Neurosurgery·J M FeinJ Parkhurst
Oct 1, 1974·Journal of Neurosurgery·J F Alksne, J H Greenhoot
Dec 1, 1972·Journal of Neurosurgery·L W Conway, L W McDonald
Oct 1, 1970·Journal of Neurosurgery·B WeirB Mielke
Mar 1, 1984·Stroke; a Journal of Cerebral Circulation·J YoshiokaR R Smith
Sep 1, 1984·Journal of Neurosurgery·T M LiszczakN T Zervas
Sep 1, 1984·Journal of Neurosurgery·T TakemaeJ F Alksne
Jan 1, 1983·Journal of Neurosurgery·V G VarsosN T Zervas
Jan 1, 1983·Journal of Neurosurgery·T M LiszczakN T Zervas
Dec 1, 1981·Journal of Neurosurgery·O P EldevikA Torvik
Jul 1, 1981·Stroke; a Journal of Cerebral Circulation·B R ClowerJ Lockard
Citations
Feb 1, 1990·Experimental Neurology·E RickelsE Reale
Aug 1, 1989·Stroke; a Journal of Cerebral Circulation·P E VinallF A Simeone
Feb 1, 1988·The Anatomical Record·B R ClowerR R Smith
Jan 1, 1994·Acta neurochirurgica·I H TekkökA Erbengi