Intracordal injection of autologous auricular cartilage in the paralyzed canine vocal fold

Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery
Byung-Joo LeeChang-Hun Lee

Abstract

Vocal fold augmentation by injectable material under direct visual control is an easy and simple operation. However, when autologous fat or bovine collagen is used, resorption creates a problem. And autologous fascia is debating about absorption now days. This study is to evaluate the histology of minced and injected autologous auricular cartilage and fat graft in the augmentation of unilateral vocal fold paralysis using a canine model. Nine dogs were operated. At first, a piece of auricular cartilage was harvested from ear and minced into tiny chips with a scalpel, and a piece of fat tissue was harvested from inguinal area and minced into tiny chips with a scalpel. Cutting off a section of the recurrent nerve paralyzed the right vocal fold. The minced cartilage and fat-paste (0.2 mL) was injected using a pressure syringe into the paralyzed thyroarytenoid muscle under direct laryngoscopy. Two animals were sacrificed at 3 days, three at 3 weeks, two at 3 months, one at 6 months, and one at 12 months. Each dog underwent laryngectomy and serial coronal sections of paraffin blocks from the posterior part of the vocal fold were made. There was no significant complication perioperatively and during follow-up. There was acute inflamma...Continue Reading

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Citations

Jul 28, 2005·HNO·M Schuster, U Eysholdt
Mar 28, 2006·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Byung-Joo LeeRobert R Lorenz
Apr 5, 2014·Journal of Voice : Official Journal of the Voice Foundation·Young Min ParkSoo-Geun Wang
Sep 21, 2007·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Erkan OzudogruBeklen Ure
Feb 10, 2016·Journal of Voice : Official Journal of the Voice Foundation·Dae-Woon KangByung-Joo Lee
Nov 1, 2011·Journal of Voice : Official Journal of the Voice Foundation·Jin-Choon LeeDong-Hoon Shin
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Apr 26, 2014·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Yun-Sung LimYong-Chan Bae
Oct 22, 2013·Yonsei Medical Journal·Seung Hoon WooHan-Sin Jeong
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Feb 6, 2020·Veterinary Surgery : VS·Lauren K LuedkeNorm G Ducharme
Nov 6, 2010·The Annals of Otology, Rhinology, and Laryngology·Adriana HachiyaDomingos Hiroshi Tsuji
Dec 29, 2020·The Laryngoscope·Anna Maria Stefanie BuchbergerKatharina Storck

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