Abstract
In this study, we aimed to compare the effectiveness and safety of NTG administration via catheter and local NTG infusion through a perforated balloon in order to prevent coronary spasm from developing during percutaneous intervention. The study began with 1:1 randomization into two groups of a total of 1688 patients scheduled for PCT. A total of 91 patients in the proximal group who developed lesions received 500 mcg NTG through a catheter, while 85 patients in the local group with lesions developed during the procedure received 500 mcg local NTG through a perforated balloon. After excluding patients who did not develop lesions during the procedure, and those without any change in the lesion with NTG application, the study was completed with 74 patients in the local group, and 70 patients in the proximal group. Both groups were similar in terms of basic characteristics. Incidences of procedure-related hypotension (10% vs 52%, P < 0.001) and tachycardia (20% vs 57%, P < 0.001) were significantly lower in the local NTG group. Success in addressing spasm was significantly higher in the local NTG than in the proximal NTG group (91.66 ± 14.09% vs 75.99 ± 16.86%, P < 0.001). Intracoronary injection with a perforated balloon, a simpl...Continue Reading
References
Aug 1, 1982·Circulation·R L FeldmanC R Conti
Jun 1, 1997·Japanese Circulation Journal·H AkiyamaR Katori
Jan 20, 2005·Heart·J W KimD J Oh
Aug 9, 2008·Journal of the American College of Cardiology·Peter OngUdo Sechtem
Apr 15, 2009·Journal of Cardiovascular Medicine·Francesco TomassiniMaria Rosa Conte
Aug 26, 2011·European Radiology·Fulvio StaculUNKNOWN Contrast Media Safety Committee of European Society of Urogenital Radiology (ESUR)
Sep 18, 2012·American Heart Journal·Dong HuangJunbo Ge
Dec 12, 2012·Journal of Investigative Medicine : the Official Publication of the American Federation for Clinical Research·Ibrahim OzdogruAbdurrahman Oguzhan
Feb 15, 2013·Korean Circulation Journal·Shi Hyun RhewMyung Ho Jeong
Mar 5, 2013·International Journal of Cardiology·Kenichi TsujitaHisao Ogawa
Feb 12, 2014·Texas Heart Institute Journal·Diego A LaraF Bennett Pearce
Sep 26, 2015·International Journal of Cardiology·Mehmet EyubogluAbdurrahman Arslan
Oct 28, 2015·BioMed Research International·Lan WangDingfeng Peng
Apr 18, 2016·International Journal of Cardiology·Chang-Bum ParkChong-Jin Kim
Mar 21, 2017·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Alec VishnevskyMichael P Savage
Apr 22, 2017·JACC. Cardiovascular Interventions·Dariusz DudekPatrick W Serruys
Oct 13, 2017·Journal of Interventional Cardiology·Yakup BalabanAli H Kayışoğlu