Intracranial aneurysms: Review of current science and management

Vascular Medicine
Gabor Toth, Russell Cerejo

Abstract

Unruptured intracranial aneurysms often have a relatively benign clinical course. Frequently, they are found incidentally during workup for an underlying, possibly related or unrelated, symptom or condition. Overall, brain aneurysms are considered to have a relatively low annual risk of rupture. However, should it occur, aneurysmal subarachnoid hemorrhage can lead to significant morbidity and mortality. Our understanding of the natural history and treatment outcomes of cerebral aneurysms has significantly increased over the last few decades, but choosing the optimal management for each patient requires the careful consideration of numerous medical, clinical and anatomic factors. The purpose of this review is to help physicians and caregivers, who may participate in the diagnosis, counseling and triage of patients with brain aneurysms, understand the basic elements of decision making. We discuss natural history, risk factors, screening, presentation, diagnosis, and their implications on aneurysm management and long-term follow-up. We also provide an overview of the risks and benefits of currently available treatment options.

References

Mar 17, 1983·The New England Journal of Medicine·G S AllenC R Transou
Aug 1, 1994·Annals of Internal Medicine·W T LongstrethG van Belle
Mar 1, 1993·Archives of Neurology·E C RapsM E Fink
Jan 2, 1997·The New England Journal of Medicine·W I Schievink
Jan 1, 1997·Stroke; a Journal of Cerebral Circulation·G J RinkelA Algra
Feb 8, 1997·Lancet·A RonkainenG Tromp
Jan 28, 1998·Stroke; a Journal of Cerebral Circulation·G J RinkelJ van Gijn
Dec 29, 1998·The New England Journal of Medicine·UNKNOWN International Study of Unruptured Intracranial Aneurysms Investigators
Sep 2, 1999·Stroke; a Journal of Cerebral Circulation·H IsoJ E Manson
May 8, 2000·Stroke; a Journal of Cerebral Circulation·T IngallR Bonita
Mar 10, 2001·Stroke; a Journal of Cerebral Circulation·C N MhurchuUNKNOWN Australasian Cooperative Research on Subarachnoid Hemorrhage Study (ACROSS) Group
Jul 5, 2001·Headache·L B MorgensternR F Frankowski
Feb 16, 2002·Neurosurgery·T R ForgetR H Rosenwasser
Jul 18, 2003·Lancet·David O WiebersUNKNOWN International Study of Unruptured Intracranial Aneurysms Investigators
Feb 27, 2004·Cephalalgia : an International Journal of Headache·A Polmear
Dec 16, 2004·Journal of Neurosurgery·L Gerard ToussaintJohn L D Atkinson
Mar 3, 2005·Journal of Neurosurgery·Madhavan L RaghavanRobert E Harbaugh
Mar 16, 2005·Archives of Neurology·Andrew M NaidechStephan A Mayer
Sep 30, 2006·Stroke; a Journal of Cerebral Circulation·Jürgen BeckVolker Seifert
May 2, 2007·Journal of Neurology, Neurosurgery, and Psychiatry·N K de RooijG J E Rinkel
Dec 1, 2007·Stroke; a Journal of Cerebral Circulation·S Claiborne JohnstonUNKNOWN CARAT Investigators
Feb 9, 2008·AJNR. American Journal of Neuroradiology·W J van RooijM Sluzewski
Feb 21, 2009·Stroke; a Journal of Cerebral Circulation·Joseph P BroderickUNKNOWN FIA Study Investigators
Nov 11, 2008·Interventional Neuroradiology : Journal of Peritherapeutic Neuroradiology, Surgical Procedures and Related Neurosciences·Hsu Huei WengYuan Hsiung Tsai
May 7, 2011·Stroke; a Journal of Cerebral Circulation·Monique H M VlakAle Algra
Jul 29, 2011·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·George K C Wong, W S Poon
Oct 8, 2011·Stroke; a Journal of Cerebral Circulation·David M HasanUNKNOWN International Study of Unruptured Intracranial Aneurysms Investigators
Jun 29, 2012·The New England Journal of Medicine·Akio MoritaTakashi Yoshimoto
Feb 21, 2013·Stroke; a Journal of Cerebral Circulation·Monique H M VlakAle Algra
Feb 23, 2013·Journal of Neuroradiology. Journal De Neuroradiologie·David M HasanWilliam L Young

❮ Previous
Next ❯

Citations

Jun 28, 2019·Journal of Neurointerventional Surgery·Francesco DianaMarcello Bartolo
Mar 12, 2020·Der Radiologe·P Dietrich
Jun 14, 2020·Biomechanics and Modeling in Mechanobiology·Frederico S TeixeiraPaul N Watton
Apr 17, 2021·Pediatric Research·Jiaxin HuangZhixian Jiang
Sep 14, 2021·Interventional Neuroradiology : Journal of Peritherapeutic Neuroradiology, Surgical Procedures and Related Neurosciences·Wei ShangYinghui Xu
Sep 28, 2021·3D Printing in Medicine·Kelsey N SommerCiprian N Ionita
Oct 2, 2021·ACS Biomaterials Science & Engineering·Emily AugustineChristopher J Bettinger
Dec 31, 2021·ANZ Journal of Surgery·Cheerag Bharatbhai PatelThirayan Muthu

❮ Previous
Next ❯

Methods Mentioned

BETA
hormone replacement therapy
imaging techniques

Software Mentioned

SVM

Related Concepts

Related Feeds

Aneurysm

Aneurysms are outward distensions or bulges that occurs in a weakened wall of blood vessels. Discover the latest research on aneurysms here.

Related Papers

Current Cardiology Reports
Deena M Nasr, Robert D Brown
TheScientificWorldJournal
Norman AjiboyeRodney Bell
Nihon rinsho. Japanese journal of clinical medicine
Masahiro YonekuraHaruhiko Kikuchi
© 2022 Meta ULC. All rights reserved