Intracranial calcification in a uremic infant with Wilms' tumor in a solitary kidney

CEN Case Reports
Hiro MatsukuraHirokazu Kanegane

Abstract

Wilms' tumor (WT), also called nephroblastoma, is an embryonic neoplasm of the developing kidney. A previously healthy Japanese female infant had WT in a single kidney without associated congenital malformations. Preoperative chemotherapy was started for the preservation of renal tissue and function. Tumor lysis syndrome, disseminated intravascular coagulopathy, and acute renal failure were accompanying. The infant needed surgical intervention and permanent replacement therapy. At the start of emergency hemodialysis, the infant had posterior reversible leukoencephalopathy syndrome because of severe hypertension. During ongoing peritoneal dialysis, the infant suffered from anemia, dietary and fluid restriction, and restriction of time and mobility. Despite alfacalcidol and calcium supplementation, the infant had secondary hyperparathyroidism and remarkably short stature. After waiting for the completion of chemotherapy, renal transplantation from the mother was completed. Successful kidney transplantation promptly corrected preexisting metabolic abnormalities causing secondary hyperparathyroidism. Subsequently, the infant often complained of headache. Computed tomographic scanning revealed calcification in the cerebellum. Refrac...Continue Reading

References

Oct 1, 1979·Journal of Pediatric Surgery·J E DeMariaB M Churchill
Dec 1, 1979·The Journal of Urology·I Penn
Nov 1, 1990·Kidney International·D S MillinerB Landing
Jan 1, 1986·Neuroradiology·B Kendall, N Cavanagh
Nov 1, 1974·The American Journal of Roentgenology, Radium Therapy, and Nuclear Medicine·W L Schey
Feb 1, 1980·Annals of Neurology·W C Koller, H L Klawans
Apr 30, 1964·The New England Journal of Medicine·R W MILLERM D MANNING
May 18, 2004·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Amanda L Ogilvy-Stuart, Helena Gleeson
Nov 30, 2005·The Oncologist·Monika L Metzger, Jeffrey S Dome
Dec 31, 2005·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Mina Matsuda-AbediniRobert S Mathias
Jun 23, 2010·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Uwe Querfeld, Robert H Mak
Mar 21, 2012·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Yevgeny GrigorievNorman E Breslow

❮ Previous
Next ❯

Related Concepts

Related Feeds

Anemia

Anemia develops when your blood lacks enough healthy red blood cells. Anemia of inflammation (AI, also called anemia of chronic disease) is a common, typically normocytic, normochromic anemia that is caused by an underlying inflammatory disease. Here is the latest research on anemia.

Blood Clotting Disorders

Thrombophilia includes conditions with increased tendency for excessive blood clotting. Blood clotting occurs when the body has insufficient amounts of specialized proteins that make blood clot and stop bleeding. Here is the latest research on blood clotting disorders.

Cancer Metabolism

In order for cancer cells to maintain rapid, uncontrolled cell proliferation, they must acquire a source of energy. Cancer cells acquire metabolic energy from their surrounding environment and utilize the host cell nutrients to do so. Here is the latest research on cancer metabolism.

Related Papers

Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association
S FletcherA M Brownjohn
Peritoneal Dialysis International : Journal of the International Society for Peritoneal Dialysis
Ayu OgawaHirofumi Makino
The Turkish Journal of Pediatrics
S Balci, B Say
© 2022 Meta ULC. All rights reserved