Intracranial carotid artery atherosclerosis: prevalence and risk factors in the general population

Stroke; a Journal of Cerebral Circulation
Daniel BosMeike W Vernooij

Abstract

Intracranial atherosclerosis is worldwide one of the leading causes of stroke. However, surprisingly little is known about its prevalence and risk factors in a community-dwelling population of white descent. In this study, we determined the prevalence and investigated risk factors of intracranial internal carotid artery calcification (ICAC) as a marker of intracranial atherosclerosis. To quantify the volume of ICAC, 2495 participants (mean age, 69.6 years) from the population-based Rotterdam Study underwent a nonenhanced computed tomography of the intracranial internal carotid arteries. We calculated the prevalence of ICAC. Next, we defined sex-specific quartiles and defined the upper quartile as severe ICAC. Risk factors of ICAC were investigated by linear and logistic multivariate modeling and were stratified by sex. The overall prevalence of ICAC was 82.2%. The median volume of ICAC was 44 mm3 and was larger in men. Age was independently associated with ICAC in both men and women. In men, excessive alcohol intake and smoking (OR, 1.74 [95% CI, 1.28-2.37] and 1.72 [95% CI, 1.10-2.70]) were strong risk factors of ICAC, whereas diabetes and hypertension were in women (OR, 2.02 [95% CI, 1.29-3.17] and 1.79 [95% CI, 1.20-2.68]). ...Continue Reading

References

Mar 15, 1990·Journal of the American College of Cardiology·A S AgatstonR Detrano
Jun 6, 2000·JAMA : the Journal of the American Medical Association·C IribarrenW S Browner
Feb 12, 2002·American Journal of Epidemiology·Rozemarijn VliegenthartJacqueline C M Witteman
Dec 6, 2003·Arteriosclerosis, Thrombosis, and Vascular Biology·Matthew A AllisonC Michael Wright
Mar 1, 2008·Stroke; a Journal of Cerebral Circulation·Mikael MazighiPierre Amarenco
Jun 7, 2008·Stroke; a Journal of Cerebral Circulation·Philip B GorelickDilip K Pandey
Jun 6, 2009·Journal of Human Hypertension·A E OdinkJ C M Witteman
Sep 4, 2010·Arteriosclerosis, Thrombosis, and Vascular Biology·Michael H CriquiNathan D Wong
Dec 18, 2010·Stroke; a Journal of Cerebral Circulation·Juan F Arenillas
Aug 27, 2011·Arteriosclerosis, Thrombosis, and Vascular Biology·Daniel BosMeike W Vernooij
Aug 31, 2011·European Journal of Epidemiology·Albert HofmanJacqueline C M Witteman

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Citations

Sep 7, 2013·Lancet·Adnan I Qureshi, Louis R Caplan
Apr 16, 2014·Clinical Neurology and Neurosurgery·Diogo C HaussenDileep R Yavagal
Nov 28, 2012·Netherlands Heart Journal : Monthly Journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation·K RitzM J Daemen
Dec 2, 2014·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Arthur H FriedlanderSanjay M Mallya
Nov 12, 2014·Acta Odontologica Scandinavica·Spyros DamaskosPaul van der Stelt
Dec 20, 2015·Medicine·Hung-Wen KaoCheng-Yu Chen
Sep 26, 2015·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Hongbing ChenJinsheng Zeng
Aug 26, 2014·Alzheimer's & Dementia : the Journal of the Alzheimer's Association·Daniel BosM Arfan Ikram
Mar 20, 2016·Scandinavian Journal of Medicine & Science in Sports·I D BrazJ P Fisher
Apr 25, 2015·European Heart Journal Cardiovascular Imaging·Daniel BosAad van der Lugt
Apr 18, 2014·Journal of Stroke·Oh Young Bang
Aug 24, 2016·European Heart Journal Cardiovascular Imaging·Lennard WolffAad van der Lugt
Sep 23, 2016·Journal of the Neurological Sciences·Gregoire BoulouisM Edip Gurol
Aug 10, 2016·Molecular Therapy : the Journal of the American Society of Gene Therapy·Wen MeiMin Liu
Oct 22, 2016·Journal of Alzheimer's Disease : JAD·Frank J WoltersM Arfan Ikram
Nov 8, 2016·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Xiao-Hong WuKa-Sing Wong
Feb 7, 2018·Cerebrovascular Diseases Extra·Richard B OlatunjiAyotunde O Ogunseyinde
Dec 21, 2017·Radiology·Arjen LindenholzJeroen Hendrikse
Oct 15, 2014·Circulation·Katja RitzMat J A P Daemen
Dec 17, 2015·Journal of the American Heart Association·Yueh-Feng SungGiia-Sheun Peng
Aug 12, 2017·Stroke; a Journal of Cerebral Circulation·Byung-Su KimGyeong-Moon Kim
Feb 6, 2017·Circulation Research·Chirantan Banerjee, Marc I Chimowitz
Mar 12, 2016·Stroke; a Journal of Cerebral Circulation·Hieab H H AdamsDaniel Bos
Dec 23, 2016·Stroke; a Journal of Cerebral Circulation·María Hernández-PérezAntoni Dávalos
Jun 18, 2017·The European Respiratory Journal·Natalie TerzikhanGuy Brusselle
Apr 10, 2019·Cephalalgia : an International Journal of Headache·Ke-Xin WenMaryam Kavousi
Sep 25, 2019·Journal of the American Heart Association·Annabelle Santos VolgmanCarl J Pepine
Jul 12, 2019·Laboratory Investigation; a Journal of Technical Methods and Pathology·Lan ZhaoQunlin Gong
May 18, 2018·Neurology·Pauline H CrollMeike W Vernooij
Apr 10, 2020·Advances in Therapy·Marina Petrova KrastevaMirjam Rachel Heldner
May 23, 2020·Current Atherosclerosis Reports·Minghua Liu, Jose Gutierrez
Sep 4, 2020·International Journal of Stroke : Official Journal of the International Stroke Society·S VoigtUNKNOWN DUST study group
Apr 21, 2018·AJNR. American Journal of Neuroradiology·A LindenholzJ Hendrikse
Oct 31, 2018·Journal of Clinical Neurology·Jeong Min KimDaeun Jeong

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