PMID: 11137657Jan 4, 2001Paper

Intracranial electroencephalographic changes in deep anesthesia

Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology
H KarasawaH Kin

Abstract

It is well known that electroencephalograms (EEGs) show electrical silence in deep anesthesia as well as brain death. This is the first report on intracranial EEG changes in deep anesthesia. We developed a new direct brain monitoring system capable of recording intracranial EEGs. This study included 13 patients with head trauma or cerebrovascular accident under deep anesthesia. The intracranial EEGs showed different patterns of wave activity in depth compared with the cortical surface. In 3 of the cases, the scalp EEG showed a flat tracing at 2.0-2.5% of isoflurane. In two of the cases, the intracranial EEGs showed electrical silence when the scalp EEG was flat. Decreasing the concentration of isoflurane to 1.5%, the intracranial EEG showed single paroxysmal appearance of 'revival' theta waves on the electrocorticogram (ECoG) or electroventriculogram (EVG). The intracranial 'revival' wave was followed by high-voltage burst-waves. In another case, at 2.0-2.5% of isoflurane, the amplitude of the waves was greatest on the EVG. There is wave activity difference in the brain depth, which the scalp EEG is unable to show. Intracranial EEGs are able to show the first signs of revival after a nearly flat tracing in deep anesthesia.

References

Jan 1, 1976·Acta neurochirurgica·G Teasdale, B Jennett
Nov 1, 1971·Anesthesiology·E I EgerT H Cromwell
Nov 1, 1981·Anesthesiology·E I Eger
Dec 1, 1981·British Journal of Anaesthesia·C Prys-Roberts
Jun 17, 1999·Journal of Neurology, Neurosurgery, and Psychiatry·J L Fernández TorreC E Polkey
Feb 1, 1965·Electroencephalography and Clinical Neurophysiology·R COOPERW G WALTER

Citations

Nov 25, 2003·Toxicology in Vitro : an International Journal Published in Association with BIBRA·J van der ValkV Baumans
Feb 17, 2006·Acta Anaesthesiologica Scandinavica·L J VossJ P M Barnard
Nov 15, 2019·Acute and Critical Care·A S M Tanim Anwar, Jae-Myeong Lee

Related Concepts

Anesthesia Procedures
Brain
Structure of Interventricular Foramen
Dose-Response Relationship, Drug
Electroencephalogram
Isoflurane
Tomography, X-Ray Computerized Axial
Glasgow Coma Scale
Anesthetic Gases
Neurosurgical Procedures

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