Intracranial ganglioglioma: MR, CT, and clinical findings in 18 patients

AJR. American Journal of Roentgenology
M CastilloJ C Hoffman

Abstract

Eighteen cases of pathologically proved intracranial gangliogliomas were reviewed to determine their MR, CT, and clinical characteristics. Seventeen patients were evaluated with contrast-enhanced CT and 14 were studied by MR imaging. Eight tumors were predominantly cystic; half of these demonstrated some contrast enhancement, and five contained calcifications. These cystic gangliogliomas were located, in order of decreasing frequency, in the cerebellum, temporal, frontal, and parietal lobes. Ten tumors were solid; eight of these showed contrast enhancement, and only one contained calcifications. Small cysts were present in one solid mass. Solid gangliogliomas occurred preferentially in the temporal lobes. On MR, the findings were nonspecific and reflected the CT findings. In one patient who received gadolinium-DTPA the lesion did not enhance. Clinically, all patients presented with nonfocal long-standing symptoms and all but three were alive an average of 18 months after the initial diagnosis. Pathologists are recognizing ganglioglioma with increasing frequency, and although its radiographic characteristics vary, it should be included in the differential diagnosis when the above-described findings are encountered.

Citations

Jan 1, 1993·Neuroradiology·M HashimotoT Masuzawa
May 1, 1994·Neuroradiology·J BerenguerJ M Mercader
Feb 1, 1996·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Y L ChangW H Lee
Aug 1, 1993·Journal of Neuro-oncology·H G KrouwerM D Prados
Jan 1, 1995·Pediatric Radiology·O R Tenreiro-PiconK Y Lau
Jan 1, 2005·European Radiology·G WilmsS Sunaert
May 12, 2007·Neurosurgical Review·Tadahisa ShonoTomio Sasaki
Nov 30, 2005·Journal of Neuro-oncology·Faruk ZorluMurat Gurkaynak
Jun 11, 2005·Clinical Neurology and Neurosurgery·Graham Joseph JeffsGeorge Tse-Hwai Wong
Dec 5, 2002·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·David G Walker, Andrew H Kaye
Jan 5, 2008·Skull Base : Official Journal of North American Skull Base Society ... [et Al.]·Sam Safavi-AbbasiMadjid Samii
Dec 1, 1994·Journal of Neurology, Neurosurgery, and Psychiatry·J ZentnerJ Schramm
Nov 14, 2001·Radiographics : a Review Publication of the Radiological Society of North America, Inc·K K Koeller, J M Henry
Sep 18, 2002·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Ji Hoon ShinDae Chul Suh
Mar 4, 2000·AJR. American Journal of Roentgenology·J M ProvenzaleR E McLendon
Jan 18, 2011·Journal of Neurosurgery·Jamie J Van GompelCaterina Giannini
Mar 1, 2002·Experimental Neurology·Neil Duggal, Robert R Hammond
Mar 18, 2009·Acta neurochirurgica·Amer F SamdaniBenjamin Carson
May 4, 2011·Clinical Neuroradiology·J FaehndrichE Hattingen
Jun 19, 2016·Clinical Imaging·Lidia Mayumi NagaeJustin M Honce
Oct 24, 2012·Magnetic Resonance Imaging Clinics of North America·Bum-soo Kim, Juan E Gutierrez
Nov 18, 2008·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·David A Westwood, Martin R MacFarlane
May 24, 2008·Clinical Neurology and Neurosurgery·Young Seok ParkJoong-Uhn Choi
Oct 19, 2006·International Journal of Radiation Oncology, Biology, Physics·Stanley L LiauwWilliam M Mendenhall
Nov 1, 1992·Surgical Neurology·H OtsuboS H Chuang
Oct 3, 2006·Seminars in Roentgenology·J Keith SmithMauricio Castillo
Jun 1, 1997·Pediatric Clinics of North America·L G Vezina
Dec 25, 2015·World Neurosurgery·G Lakshmi PrasadVaishali Suri
Sep 1, 1996·Arquivos de neuro-psiquiatria·P T Brainer-LimaR Marino Júnior
Aug 1, 1992·Neurosurgery·S F HaddadJ C VanGilder
Feb 23, 2012·Neurosurgery·Derek G SouthwellEdward F Chang
Nov 1, 2001·Topics in Magnetic Resonance Imaging : TMRI·V M RungeJ R Jinkins
Feb 7, 2021·World Neurosurgery·Freddy J Salge-ArrietaLuis Ley-Urzáiz
Jul 1, 2017·NMC Case Report Journal·Nayuta HigaKazunori Arita
May 30, 1991·The New England Journal of Medicine·P M Black
Nov 27, 2021·British Journal of Neurosurgery·Guangbiao QinYunlin Li

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.