PMID: 6168166May 1, 1981Paper

Intracranial germ cell tumor indicating a high level of alpha-fetoprotein (AFP)

Acta Pathologica Japonica
M TsuchiyamaH Kitamura

Abstract

An autopsy case of intracranial and extrapineal tumor is reported. The tumor, detected 2 years and 4 months before death, was an ectopic pinealoma (germ cell tumor) and showed elevated serum alpha-fetoprotein (AFP) of 48,000 ng/ml. Histologically, intra- and extracellular PAS-positive hyaline globules were observed in the tumor. The tumor tissues of the paraffin sections revealed a bright positive fluorescence for AFP with indirect immunofluorescence method. Besides, there were generalized metastases in this case.

References

Jan 1, 1969·The Journal of Pathology·A Borit
Sep 1, 1974·Brain : a Journal of Neurology·M B Camins, L A Mount
Jan 1, 1968·Acta Pathologica Et Microbiologica Scandinavica·J Bestle
Aug 1, 1966·Archives of Surgery·R H NishiyamaJ H Simrall
Jul 1, 1954·The Journal of Pathology and Bacteriology·D S RUSSELL
Apr 1, 1961·Neurology·N KAGEYAMA, R BELSKY

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Citations

Nov 1, 1984·Journal of Neurosurgery·H NaganumaM Tamura

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