Intracranial melanotic schwannomas: a rare variant with unusual adherent features

Journal of Neuro-oncology
D MahatoA Quiñones-Hinojosa

Abstract

Intracranial melanotic schwannomas (IMSch) are extremely rare nerve sheath tumors with features of Schwann cells that produce melanin. After a thorough review of the available literature since 1967, we report not only the 20th case of IMSch but a comprehensive modern-era analysis of radiographic and histological key-points to be considered when diagnosing and treating patients with this rare known entity. This is the case of a 43 years-old woman who presented with severe headaches 9 years ago (2008). At that time, MRI of the brain showed a 1.5 × 1.4 cm lesion at the level of the left cerebellar peduncle without any evidence of edema, mass effect or hydrocephalus. Given that the patient was neurologically intact, a conservative management with serial MRIs was recommended. Patient stopped following up due to the absence of symptoms. Over the course of the past year, patient noted mild left sided hearing loss and facial weakness, as well as some balance instability that progressed over the last 3 months. Given the presentation and progression of these signs and symptoms, a new MRI was performed in which considerable growth of the lesion was identified, measuring 2.5 × 2.8 × 2.6 cm with mass effect on the pons and the inferior four...Continue Reading

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Citations

May 10, 2018·Pathology Oncology Research : POR·Xiao-Li Li, Shun-Dong Dai
May 17, 2019·The Neuroradiology Journal·Ali Alamer, Donatella Tampieri
May 6, 2021·Surgical Neurology International·Dallas J SoylandShawn M Vuong
Sep 25, 2021·Clinical Nuclear Medicine·Xiangliu OuYangXiaoming Zhang

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