Intracranial Vessel Wall MRI in Cryptogenic Stroke and Intracranial Vasculitis

Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association
Virginie DestrebecqGilles Naeije

Abstract

Intracranial vasculopathies easily elude classic stroke work-up. We aim in this work to show that vessel wall-MRI could prove an efficient alternative to digital subtraction angiography for the diagnosis of intracranial vasculopathies by identifying intracranial arterial vessel walls anomalies and contrast enhancement, suggestive of angiitis of the central nervous system. Clinical and imaging characteristics of stroke patients diagnosed with primary angiitis of the central nervous system based on vessel wall-MRI were retrospectively reviewed and the clinical and imaging features of angiitis associated with intracranial vessel walls anomalies and contrast enhancement detailed. Twenty patients were included (mean age was 59 years old). All patients were admitted for focal neurological deficits of sudden onset that were recurrent in 13 subjects. Cognitive impairment, headache and seizures occurred in, respectively, 13, 5, and 2 patients. Cerebrospinal fluid analysis was abnormal in 15 patients. In MRI, FLAIR sequences showed ischemic infarcts in 20 patients and DWI showed acute infarct in 15 patients. Digital subtraction angiography was performed in 11 patients and disclosed proximal and distal multifocal stenosis in 10 patients a...Continue Reading

Citations

Nov 13, 2020·The Neurologist·Matthew M PadrickOana M Dumitrascu
Nov 14, 2020·Current Opinion in Rheumatology·Serdar ArslanOsman Kizilkilic
Apr 28, 2021·Neuroimaging Clinics of North America·Kambiz NaelDavid S Liebeskind
Sep 28, 2021·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·Federico MazzacaneAndrea Morotti

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