Intracystic application of mebendazole solution in the treatment of liver hydatid disease. Preliminary report of two cases

European Surgical Research. Europäische Chirurgische Forschung. Recherches Chirurgicales Européennes
K ErzurumluM Kesim

Abstract

Mebendazole, a derivate of benzimidazole, is commonly used for the treatment of hydatid disease in patients at high operative risk and/or to prevent secondary hydatidosis. In this study, 2 cases of liver hydatid disease, in which mebendazole was used both orally and for intracystic application are presented. These cases have been treated by percutaneous drainage and videolaparoscopic methods. Mebendazole solution at a concentration of 2.4 micrograms/ml was injected into the cyst. For a period of 6 months 50 mg/kg/day oral treatment was given. At the end of a 6- to 9-month period, the total recovery was observed. This is the first report of mebendazole pair-treatment in the literature.

Citations

Mar 3, 2005·Journal of Gastroenterology and Hepatology·Cafer PolatKenan Erzurumlu
Jan 1, 2009·Journal of Parasitology Research·Razika Zeghir-BouteldjaChafia Touil-Boukoffa
Oct 3, 2003·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Raymond A SmegoM Asim Beg
Feb 15, 2005·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Raymond A Smego, Peter Sebanego
Apr 16, 2005·World Journal of Gastroenterology : WJG·Kenan ErzurumluMurat Hokelek
Aug 13, 2014·Annals of Surgical Treatment and Research·Kagan KarabulutKenan Erzurumlu
Aug 7, 2003·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Yahya PaksoyAhmet Arslan

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