Intracytoplasmic lumina in human oviduct epithelium

Ultrastructural Pathology
H HagiwaraT Fujimoto


Intracytoplasmic lumina (ICL) in human oviduct epithelium were investigated with transmission electron microscopy. ICL were found in 43 out of 60 cases examined. They were ultrastructurally characterized by microvilli lining the lumina, periodic acid-thiocarbohydrazide-silver proteinate (PA-TCH-SP) staining-positive finely granular material in the lumina, and secretory vesicles in the cytoplasm surrounding the lumina. Although ICL were observed at various heights within the epithelium, they were mainly seen in basally located cells that did not face the oviduct lumen. Various stages of formation and development of ICL were observed in the basally located epithelial cells with secretory activities. Primary ICL were originated in the cytoplasm where the secretory granules were aggregated with smooth-surfaced tubular vesicles. Electron microscopic observations after PA-TCH-SP staining revealed that ICL were formed by fusion of the secretory granules with the tubular vesicles. ICL were enlarged into round profiles by further fusion of secretory granules and tubular vesicles, and subsequently opened to the oviduct lumen, or fused to each other to develop into large extracellular cysts within the epithelium.


Nov 1, 1979·Journal of Ultrastructure Research·L E Ericson
Sep 1, 1979·Human Pathology·J AlroyV E Gould
Dec 1, 1977·Journal of Ultrastructure Research·L RemyG Fayet
Sep 1, 1978·Cancer·L JohnsonG Jolly
Jun 1, 1988·The American Journal of Surgical Pathology·J Y RoN G Ordóñez
May 1, 1989·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·J DelladetsimaC Kittas
Jan 1, 1985·Virchows Archiv. B, Cell Pathology Including Molecular Pathology·L Remy, J Marvaldi
Jan 1, 1986·British Journal of Clinical Pharmacology·A M Breckenridge
Aug 1, 1967·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·B Monis, H D Dorfman
Oct 1, 1981·Ultrastructural Pathology·M Sobrinho-SimõesV E Gould
Dec 1, 1994·Archives of Histology and Cytology·H Hagiwara
May 1, 1994·Ultrastructural Pathology·K L HoJ H Garcia
Apr 1, 1993·Pathology, Research and Practice·G QuinonezM Diocee


Oct 10, 2014·Pediatric and Developmental Pathology : the Official Journal of the Society for Pediatric Pathology and the Paediatric Pathology Society·Eric P WartchowGary W Mierau
Sep 10, 2013·Human Mutation·K Joeri van der VeldeSven C D van Ijzendoorn
May 6, 2016·Cytopathology : Official Journal of the British Society for Clinical Cytology·A SuzukiA Miyauchi

Related Concepts

Periodic acid-thiocarbohydrazide-silver proteinate
Fallopian Tubes
Electron Microscopy
Ovarian Diseases
Periodic Acid (HIO4)

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Alzheimer's Disease: MS4A

Variants within the membrane-spanning 4-domains subfamily A (MS4A) gene cluster have recently been implicated in Alzheimer's disease in genome-wide association studies. Here is the latest research on Alzheimer's disease and MS4A.

Pediculosis pubis

Pediculosis pubis is a disease caused by a parasitic insect known as Pthirus pubis, which infests human pubic hair, as well as other areas with hair including eye lashes. Here is the latest research.

Rh Isoimmunization

Rh isoimmunization is a potentially preventable condition that occasionally is associated with significant perinatal morbidity or mortality. Discover the latest research on Rh Isoimmunization here.

Genetic Screens in iPSC-derived Brain Cells

Genetic screening is a critical tool that can be employed to define and understand gene function and interaction. This feed focuses on genetic screens conducted using induced pluripotent stem cell (iPSC)-derived brain cells. It also follows CRISPR-Cas9 approaches to generating genetic mutants as a means of understanding the effect of genetics on phenotype.

Enzyme Evolution

This feed focuses on molecular models of enzyme evolution and new approaches (such as adaptive laboratory evolution) to metabolic engineering of microorganisms. Here is the latest research.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Pharmacology of Proteinopathies

This feed focuses on the pharmacology of proteinopathies - diseases in which proteins abnormally aggregate (i.e. Alzheimer’s, Parkinson’s, etc.). Discover the latest research in this field with this feed.

Alignment-free Sequence Analysis Tools

Alignment-free sequence analyses have been applied to problems ranging from whole-genome phylogeny to the classification of protein families, identification of horizontally transferred genes, and detection of recombined sequences. Here is the latest research.

Related Papers

Journal of Pediatric Gastroenterology and Nutrition
Oliver J OatmanMitchell D Shub
Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research
K KagitaniS Okada
Digestive Diseases and Sciences
Jennifer C BurgisJohn A Kerner
Pediatrics and Neonatology
Ming-Chou ChiangMing-Wei Lai
Taiwanese Journal of Obstetrics & Gynecology
Chih-Ping ChenWayseen Wang
© 2021 Meta ULC. All rights reserved