Intraductal growth of a nonfunctioning endocrine tumor of the pancreas

Journal of Gastroenterology
Tomotaka AkatsuMasaki Kitajima

Abstract

Intraductal growth of nonfunctioning endocrine tumors of the pancreas may be very rare, and our survey of literature shows only two cases have been described. We report a case of a 43-year-old man with a nonfunctioning endocrine tumor of the pancreas that uniquely grew within the lumen of the main pancreatic duct (MPD) without ductal involvement and completely obstructed the MPD. Endoscopic ultrasonography (EUS) and endoscopic retrograde cholangiopancreatography (ERCP) were very helpful to delineate the intraductal growth of the tumor and to determine the resection line of the pancreas. A nonfunctioning pancreatic endocrine tumor is important to consider on differential diagnoses when complete obstruction of the MPD is demonstrated on ERCP. It is speculated that the tumor originated from precursor cells of the pancreatic duct or islet cells adjacent to the MPD and slowly proliferated within the lumen of the MPD.

Citations

Sep 19, 2009·Endocrine Pathology·Runjan Chetty, Ihab El-Shinnawy
Sep 21, 2006·Pathology International·Rin YamaguchiMasamichi Kojiro
May 24, 2007·Journal of Hepato-biliary-pancreatic Surgery·Mitsuhiro InagakiShinichi Kasai
Dec 17, 2016·The American Journal of Surgical Pathology·Olca BasturkDavid S Klimstra
Mar 25, 2011·Virchows Archiv : an International Journal of Pathology·Thomas WalterJean-Yves Scoazec
Nov 17, 2016·Surgical Case Reports·Kouki ImaokaHideto Sakimoto
Aug 24, 2012·AJR. American Journal of Roentgenology·Aparna BalachandranChuslip Charnsangavej
Mar 6, 2009·Archives of Pathology & Laboratory Medicine·Paola CapelliAldo Scarpa

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