Intraductal papillary neoplasia of the liver associated with hepatolithiasis

Hepatology : Official Journal of the American Association for the Study of Liver Diseases
T C ChenYuji Nimura

Abstract

Intraductal papillary growth of neoplastic biliary epithelia with a fine fibrovascular stalk (intraductal papillary neoplasia of liver [IPN-L]) resembling intraductal papillary mucinous neoplasm of pancreas is occasionally associated with hepatolithiasis. In this study, 136 cases of hepatolithiasis in Taiwan, between January 1998 and March 2000, and an additional 21 cases of IPN-L before December 1998, were examined histologically. IPN-L was found in 41 of 136 hepatolithiasis cases (30.1%). Sixty-two IPN-L cases (42 women and 20 men; age range, 59.8 +/- 10 years) were divided into 4 types (type 1, IPN-L with low-grade dysplasia, 23 cases; type 2, IPN-L with high grade dysplasia, 11 cases; type 3, IPN-L with in situ and microinvasive carcinoma, 13 cases; and type 4, IPN-L of types 2 and 3 with distinct invasive carcinoma, 15 cases). Intraductal spreading and glandular involvement were commonly observed in all types. About half of types 3 and 4 cases had mucobilia, and mucinous carcinoma was variably found in two thirds of group 4 patients. IPN-L frequently showed variable gastroenteric differentiation such as goblet cells and foveolar and colon-like metaplasia. IPN-L with goblet cells and colon-like metaplasia was frequently ass...Continue Reading

References

Sep 1, 1990·Journal of Gastroenterology and Hepatology·Hiroshi KurumayaYasuni Nakanuma
Jan 1, 1987·The British Journal of Surgery·N S HadjisL H Blumgart
Jan 1, 1986·The American Journal of Surgical Pathology·J Albores-SaavedraD E Henson
Sep 1, 1972·Journal of Clinical Pathology·P J GallagherM J Mitchinson
Dec 31, 1998·Journal of Gastroenterology and Hepatology·M F Chen
Apr 27, 1999·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·S RadaevaA E Sirica
Dec 29, 1999·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·K S SuhS W Kim
Jun 30, 2000·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Y K KangW H Kim
Dec 20, 2000·Current Surgery·J M McDonaldA Beitler

Citations

Dec 14, 2004·Der Pathologe·Günter KlöppelJ Lüttges
Mar 27, 2009·Journal of Hepato-biliary-pancreatic Surgery·Yoshitsugu NakanishiSatoshi Kondo
Sep 7, 2005·Journal of Gastroenterology·Yasumi KatsutaTeruo Takano
Jul 13, 2011·Surgery Today·Masakazu Yamamoto, Shun-ichi Ariizumi
Oct 9, 2007·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Shuichiro UchiyamaKazuhiro Kondo
May 23, 2012·Annals of Nuclear Medicine·Aisheng DongChangjing Zuo
Feb 25, 2005·Gastrointestinal Endoscopy·Yasuharu YamaguchiShin-ichi Takahashi
Mar 23, 2011·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Tsan-Hua YuYung-Ming Jeng
Apr 26, 2011·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Yoh ZenBernard Portmann
Jun 3, 2006·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Yoh ZenYasuni Nakanuma
Apr 14, 2007·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Yoh ZenYasuni Nakanuma
Dec 25, 2002·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Miguel R ArguedasMichael B Fallon
Aug 30, 2002·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Rosmawati MohamedJames M Neuberger
Oct 13, 2006·Current Opinion in Gastroenterology·Jay H Lefkowitch
Jul 13, 2006·International Anesthesiology Clinics·Michael A Ramsay
Oct 29, 2013·European Journal of Anaesthesiology·Pascal FauconnetEduardo Schiffer
Oct 11, 2012·Surgical Laparoscopy, Endoscopy & Percutaneous Techniques·Bum-Soo KimKwang-Ro Joo
Mar 3, 2004·Pathology International·Koichi TsuneyamaYasuni Nakanuma
Jan 15, 2004·Pathology International·Tadashi Terada, Masami Taniguchi
Apr 14, 2005·Pathology International·Takahiko FujiiYasuni Nakanuma
Nov 9, 2007·Pathology International·Yuji IshibashiYae Kanai
Aug 18, 2010·Pathology International·Hee Jung ParkSeong Hyun Kim
Mar 18, 2003·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Jae Hoon LimHyo Keun Lim
Jan 1, 2008·Case Reports in Gastroenterology·Atsushi NanashimaTakeshi Nagayasu
Jun 3, 2004·Annals of Surgical Oncology·Chun-Nan YehMiin-Fu Chen
Sep 30, 2006·Annals of Surgical Oncology·Chun-Nan YehMiin-Fu Chen
Oct 25, 2011·AJR. American Journal of Roentgenology·Jae Hoon LimYasuni Nakanuma
Mar 12, 2008·World Journal of Gastroenterology : WJG·Junpei HayashiMitsuhiko Moriyama
Oct 10, 2013·World Journal of Gastroenterology : WJG·Hirohide SatoYasuni Nakanuma
Dec 31, 2010·World Journal of Hepatology·Yasuni NakanumaHiroko Ikeda
Apr 20, 2014·World Journal of Gastroenterology : WJG·Agnieszka BudzynskaMichal Mazurkiewicz
Mar 13, 2009·Southern Medical Journal·Akshra VermaIkechukwu Uzoaru

Related Concepts

Related Feeds

Astrocytes

Astrocytes are glial cells that support the blood-brain barrier, facilitate neurotransmission, provide nutrients to neurons, and help repair damaged nervous tissues. Here is the latest research.