Intradural, extramedullary spinal sarcoidosis: report of a rare case and review of the literature

The Spine Journal : Official Journal of the North American Spine Society
Bernhard SchallerHans C Ludwig

Abstract

Spinal sarcoidosis represents a rare subgroup of neurosarcoidosis. Most spinal sarcoid lesions are intramedullary, and only eight cases of intradural, extramedullary sarcoid lesions have been reported hitherto. We describe the complete entity of intradural, extramedullary spinal sarcoidosis. A 39-year-old woman presented with a 2-year history of slowly progressive numbness and paresthesia of the right medial upper arm followed by brachialgia and cephalgia. Magnetic resonance imaging revealed an intradural extramedullary T1 isointense and T2 hyperintense mass lesion near the right C3 nerve root exit C3, extending into the right neuroforamen. The cervical cord was not severely compressed. The mass lesion showed a high T2 signal. After intravenous administration of gadolinium-diethylenetriaminepentaacetic acid, there was marked enhancement of the process. The patient underwent a C2 to C3 laminoplasty and total resection of the intradural extramedullary tumor. The lesion encroached along the right neuroforamen, involving the C3 nerve root, and was grossly adherent to some of the rootlets. Histopathological examination of the specimen showed a noncaseating granulomatosis consistent with sarcoidosis. Postoperative testing did not rev...Continue Reading

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Citations

Mar 26, 2014·The American Journal of Medicine·Florentina BerianuYaw Amoateng-Adjepong
Oct 23, 2014·Journal of Craniovertebral Junction and Spine·Nora Sandu, Bernhard Schaller
Mar 10, 2010·Spinal Cord·T TeradaT Hata
Nov 25, 2006·Der Radiologe·I GrunwaldW Reith
Oct 15, 2011·Journal of Orthopaedic Science : Official Journal of the Japanese Orthopaedic Association·Yasuyuki ShiraishiYuichi Hoshino
Jun 10, 2008·Clinics in Chest Medicine·Elyse E Lower, Kenneth L Weiss
Jan 7, 2011·Molecular Medicine·Nora SanduBernhard Schaller
Jun 10, 2017·Current Opinion in Pulmonary Medicine·Daan FritzMatthijs C Brouwer
Apr 3, 2020·Journal of Clinical Medicine·Radjiv GoulabchandPhilippe Guilpain
Jan 19, 2012·International Journal of Dermatology·Frederick A PereiraKaren Karsif
Feb 26, 2020·Journal of Clinical Pathology·Jessie M Wu, Gulisa Turashvili
Aug 31, 2019·Case Reports in Orthopedics·Sho IshiwataHirotaka Chikuda
Jul 17, 2021·Journal of the American Academy of Orthopaedic Surgeons. Global Research & Reviews·Louis A MagdonChristina W Cheng

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