Intragastric microbial colonization in common disease states of the stomach and duodenum.

Annals of Surgery
R L Nichols, J W Smith

Abstract

Forty-nine patients undergoing elective or emergent gastric surgery have been included in this study. Gastric needle aspiration was performed at the time of surgery in each case, followed by qualitative aerobic and anaerobic bacteriologic analysis. In 18 patients undergoing elective operation for chronic nonobstructing duodenal ulcer a gastric microflora was present in only three patients and no postoperative wound infections were observed. In 29 of 31 patients, in the other groups of patients with bleeding or obstructing duodenal ulcer or in those with gastric ulcer or malignancy, intragastric micro-organisms were present. Six of the 7 postoperative wound infections which developed in these groups of patients were due to one of the same bacteria isolated at the time of original needle aspiration. It appears that the endogenous intragastric microflora is a significant factor in the development of postoperative wound sepsis following gastric resection, in those groups of patients with a compromise of their normal gastric antibacterial inhibitory mechanisms.

Citations

Aug 1, 1985·European Journal of Clinical Microbiology·C MarneA Sitges-Serra
Jul 1, 1989·Diagnostic Microbiology and Infectious Disease·R L Nichols
Jul 1, 1996·American Journal of Surgery·R L Nichols
Apr 1, 1995·Journal of Internal Medicine·E Husebye
May 1, 1988·Antimicrobial Agents and Chemotherapy·S M Finegold, H M Wexler
Sep 1, 1988·European Journal of Epidemiology·N MozzilloA Formato
Aug 1, 1986·Gastrointestinal Endoscopy·J M GreifR Riding
Jan 1, 1982·American Journal of Surgery·R L NicholsJ LoCicero
May 15, 1984·The American Journal of Medicine·R L Nichols
Mar 1, 1981·The American Journal of Medicine·R L Nichols
Mar 18, 2000·Journal of Chemotherapy·P S Barie
Feb 1, 1996·Journal of Chemotherapy·M Hedberg, C E Nord
Oct 1, 1985·The Annals of Thoracic Surgery·J LoCicero, R M Vanecko
May 1, 1982·American Journal of Surgery·J BoeyG B Ong
Nov 1, 1979·American Journal of Surgery·R T LewisF M Wiegand
Sep 1, 1982·The British Journal of Surgery·S E WilsonR A Williams
Mar 8, 2007·Emergency Radiology·Ashwin AsraniRathachai Kaewlai
May 22, 2007·The British Journal of Surgery·Y MohriUNKNOWN Mie Surgical Infection Research Group
Sep 1, 1982·Scandinavian Journal of Gastroenterology·L K EnanderA Schwan
Jul 24, 1998·Journal of Computer Assisted Tomography·B C KangJ H Kim
Jun 1, 1989·Journal of Chemotherapy·R L Nichols
Sep 1, 1984·Pharmacotherapy·T G Burnakis
Feb 1, 1983·Current Problems in Surgery·J T DipiroW O Griffen

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.