Intrahepatic bile duct adenoma in a patient with chronic hepatitis B accompanied by elevation of alpha-fetoprotein

Clinical and Molecular Hepatology
Jem Ma AhnByung Chul Yoo

Abstract

A 51-year-old male patient with chronic hepatitis B was referred to our hospital due to a 1-cm liver nodule on ultrasonography. Alpha-fetoprotein (AFP) was slightly elevated. The nodule showed prolonged enhancement on dynamic liver magnetic resonance imaging and appeared as a hyperintensity on both diffusion-weighted and T2-weighted imaging. The nodule was followed up because it was small and typical findings of hepatocellular carcinoma (HCC) were not observed in the dynamic imaging investigations. However, liver contrast-enhanced ultrasonography performed 1 month later showed enhancement during the arterial phase and definite washout during the delayed phase. Also, AFP had increased to over 200 ng/mL even though AST and ALT were decreased after administering an antiviral agent. He was presumptively diagnosed as HCC and underwent liver segmentectomy. Microscopy findings of the specimen indicated bile duct adenoma. After resection, the follow-up AFP had decreased to within the normal range. This patient represents a case of bile duct adenoma with AFP elevation mimicking HCC on contrast-enhanced ultrasonography.

References

Mar 1, 1978·Archives of Surgery·C ChoL S Rogers
Mar 1, 1992·Journal of Computer Assisted Tomography·J YoshikawaT Takashima
Sep 1, 1988·The American Journal of Surgical Pathology·G S AllaireI A Sesterhenn
Jul 1, 1996·The American Journal of Surgical Pathology·P S BhathalZ D Goodman
Oct 19, 1999·Journal of Computer Assisted Tomography·T TajimaK Masuda
Sep 9, 2006·Radiation Medicine·Eriko MaedaKuni Ohtomo
Sep 3, 2010·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·You Sung KimDong Goo Kim
May 11, 2012·World Journal of Clinical Oncology·Futa KogaWataru Ono
May 23, 2012·Journal of Clinical Ultrasound : JCU·Andrea GiannettiFrancesco Giangregorio
Sep 18, 2013·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Chansik AnYoon Jung Choi

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Citations

Mar 5, 2020·Japanese Journal of Radiology·Ryoji TatsumiYoshiyasu Karino

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