PMID: 2496280Apr 1, 1989Paper

Intrahepatic bile duct changes in human hepatosplenic schistosomiasis mansoni

Liver
M R ViannaT de Brito

Abstract

Wedge liver biopsies of 132 patients with hepatosplenic mansonian schistosomiasis were studied and divided in two groups according to the presence (Group I - 69 cases) or absence (Group II - 63 cases) of markers of the actual presence of the parasite in the liver tissue. Histological variables indicating bile duct injury were analysed in each case: periductal fibrosis, hyperplasia of the bile duct epithelium, bile duct degeneration, and marginal ductular proliferation. The presence of one or more of these variables defined two sub-groups: A - bile duct lesions present (73 cases), and B - bile duct lesions absent (59 cases). The variables "bile duct degeneration" and "ductular proliferation" were related to the actual presence of the parasite in the host. In 55.3% of all cases of human mansonian schistosomiasis a spectrum of injuries to the bile ducts was present. Epithelial hyperplasia alone or associated with patterns of mucopolysaccharide production was observed in 87.6% cases of the Sub-group A. The bile ducts changes in mansonian schistosomiasis are close to those described in liver fluke infestations such as clonorchiasis, fascioliasis and opistorchiasis. Statistical analysis revealed that high mucopolysaccharide productio...Continue Reading

References

Aug 23, 1979·Virchows Archiv. A, Pathological Anatomy and Histology·W Acosta-FerreiraL M Falconi
Oct 1, 1979·International Journal for Parasitology·A J Bedi, H Isseroff
Dec 16, 1977·Science·H IsseroffD Reino
Jan 1, 1987·Virchows Archiv. B, Cell Pathology Including Molecular Pathology·W ThamavitM A Moore
Apr 1, 1986·Human Pathology·J H Smith, J D Christie
Jan 1, 1987·International Archives of Allergy and Applied Immunology·G M Abdul-Aal, A M Attallah
Nov 1, 1985·The American Journal of Tropical Medicine and Hygiene·G V Hillyer
Jul 1, 1955·The Journal of Pathology and Bacteriology·P C HOU

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Citations

Jan 13, 2017·Arquivos De Gastroenterologia·Ana Virgínia Matos Sá BarretoClarice Neuenschwander Lins de Morais
Nov 21, 2009·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Onofrio A CatalanoPeter F Hahn
Aug 20, 2010·Memórias do Instituto Oswaldo Cruz·Clarice Neuenschwander Lins de MoraisSilvia Maria Lucena Montenegro
Nov 30, 2011·Memórias do Instituto Oswaldo Cruz·Ana Lúcia Coutinho DominguesEdmundo Pessoa de Almeida Lopes
Aug 20, 2010·Memórias do Instituto Oswaldo Cruz·Luciano Fernandes PereiraRozangela Maria de Almeida Fernandes Wyszomirska
Mar 1, 1990·Revista Do Instituto De Medicina Tropical De São Paulo·L C GayottoI V Souza
Jan 18, 2006·Revista Da Sociedade Brasileira De Medicina Tropical·Ludmila Oliveira, Zilton A Andrade
Dec 6, 2018·Revista Da Sociedade Brasileira De Medicina Tropical·Fabiana Letícia da SilvaFred Luciano Neves Santos
Oct 1, 2010·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Catherine H McCrann, James L Boyer

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