PMID: 18421191Apr 19, 2008Paper

Intrahepatic splenosis with severe iron deposition presenting with atypical magnetic resonance images

Internal Medicine
Tomoki NakajimaEiichi Konishi

Abstract

An intrahepatic mass was incidentally found in a 41-year-old man with a history of a traffic accident injury which resulted in removal of a ruptured spleen. Hepatic splenosis was considered in the differential diagnosis but magnetic resonance imaging showed hypointensity on T2-weighted images, atypical for normal spleen. Histologically, the mass showed sinusoidal structures and lymphoid follicular aggregates. Immunohistochemical study showed that the phenotype of the vascular lining cells was CD8-positive, CD31-positive, and CD34 negative, the pattern diagnostic for ectopic spleen. In addition, severe iron deposition was histologically demonstrated, which was considered as the cause of the hypointense T2-weighted images.

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Nov 15, 2011·Journal of Gastric Cancer·Kyu Chul KangSeong Jin Park
Nov 2, 2018·Scottish Medical Journal·Bella SmolenTarek Saadi
Feb 28, 2019·The Journal of International Medical Research·Xianzhang LuoNianqiao Gong
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Feb 28, 2020·Abdominal Radiology·Shuichi KawadaKouichi Mori
Oct 11, 2012·Surgical Laparoscopy, Endoscopy & Percutaneous Techniques·Kun LiuXiujun Cai
Jun 30, 2018·World Journal of Surgical Oncology·Zefeng XuanShusen Zheng

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