Intrahepatic vein for fetal blood sampling: one center's experience

American Journal of Obstetrics and Gynecology
Abimbola J Aina-MumuneyJude P Crino

Abstract

The objective of the study was to examine 1 center's experience with fetal blood sampling via the fetal intrahepatic vein (IHV) and cordocentesis. Consecutive IHV and cordocentesis procedures between July 1987 and February 2006 were compared with respect to success rates, streaming at the sampling site, nonreassuring fetal heart rate (NRFHR), or need for urgent delivery post procedure. A subanalysis of cases with fetal thrombocytopenia was performed. Data were analyzed using Fisher's exact and Student t tests. Two hundred ten procedures (130 IHV samplings and 110 cordocenteses) were identified. Success rates were significantly higher with IHV sampling than with cordocentesis (84.6% vs 69.1%, P = .004). Streaming from the sampling site occurred after 0.79% of IHV procedures vs 30.8% of cordocenteses (P < .0001). There was no difference between IHV and cordocentesis in the incidence of NRFHR or need for immediate delivery. Twenty-five cases of fetal thrombocytopenia (20 sampled via IHV, 5 by cordocentesis) were identified. Streaming from the sampling site occurred in 0 of 20 IHV cases vs 2 of 5 cordocentesis cases (40%) (P = .03). IHV has a significantly lower rate of streaming from the sampling site, compared with cordocentesis....Continue Reading

References

May 1, 1989·European Journal of Obstetrics, Gynecology, and Reproductive Biology·C DonnerF Rodesch
Aug 15, 1983·American Journal of Obstetrics and Gynecology·F DaffosF Forestier
May 1, 1995·Fetal Diagnosis and Therapy·C P Weiner
Feb 1, 1995·American Journal of Obstetrics and Gynecology·M J PaidasJ B Bussel
Nov 3, 1998·The Journal of Obstetrics and Gynaecology Research·A ChinnaiyaC T Meng
May 20, 2000·American Journal of Obstetrics and Gynecology·R M SilverJ R Scott
Apr 23, 2002·American Journal of Obstetrics and Gynecology·Timothy G OvertonNicholas M Fisk

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Citations

Jun 27, 2019·The Journal of Obstetrics and Gynaecology Research·Jun SasaharaNobuaki Mitsuda
Oct 19, 2020·Molecular Therapy : the Journal of the American Society of Gene Therapy·Rachel SagarAnna L David

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