Intraindividual Keratoconus Progression

Klinische Monatsblätter für Augenheilkunde
Susanne GoebelsA Langenbucher

Abstract

Introduction Keratoconus is a typically bilateral, progressive-extending corneal disease. The aim of this work is to evaluate the intraindividual progression of keratoconus. Patients and Methods This single-center retrospective study of disease progression based on topographic data from non-operated keratoconus patients (n = 48) was examined over a period of two years. Seven topographical keratoconus indices derived from Scheimpflug tomography were used to compare both the initial findings, as well as the progression of the fellow eyes. Results The mean observation period was 3.3 ± 0.9 years. The initial findings illustrated that a pair of eyes did not correlate with each other (p > 0.05). When comparing baseline and the progression of the individual indices, a negative correlation was found for all indices (p < 0.05). Progression and age did correlate for index smallest radius (Rmin, (R = 0.376, p = 0.008) and index of height decentration (IHD, R = 0.291, p = 0.045). Regarding the intraindividual progression, we found a weak correlation to the index of surface variance (ISV, R = - 0.399, p = 0.005), index of vertical asymmetry (IVA, R = - 0.291, p = 0.045) and the keratoconus index (KI, R = 0.307, p = 0.038). Conclusions The i...Continue Reading

Citations

Jun 29, 2021·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·B SeitzE Flockerzi
Nov 4, 2021·Klinische Monatsblätter für Augenheilkunde·Kathrin RichterTimo Eppig

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