Intralobar pulmonary sequestration associated with marked elevation of serum carbohydrate antigen 19-9

The Annals of Thoracic Surgery
Satoshi AmbiruAkihiko Takeshi

Abstract

This report describes a 62-year-old man who experienced elevated serum carbohydrate antigen 19-9 (CA19-9) levels (>500 U/mL) for 4 years, and was finally diagnosed with right intralobar pulmonary sequestration. Surgery confirmed the presence an aberrant artery arising from the descending thoracic aorta and entering the right lower lobe basal segment. Immunohistochemistry demonstrated markedly positive staining of CA19-9 in the ciliated cylindrical epithelia, alveoli, and mucus in the cysts. After pulmonary resection, CA19-9 levels decreased to within a normal range. Therefore, the cause of the elevated serum CA19-9 levels in this case was almost certainly due to intralobar pulmonary sequestration.

References

Nov 5, 2002·Internal Medicine·Hisanaga YagyuTakeshi Matsuoka
Mar 28, 2007·Journal of Clinical Laboratory Analysis·Takahide KodamaMorio Ohtsuka

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Citations

Sep 4, 2015·Journal of Nippon Medical School = Nippon Ika Daigaku Zasshi·Jiajia DongKeqing Shi
Mar 4, 2014·Annals of Thoracic and Cardiovascular Surgery : Official Journal of the Association of Thoracic and Cardiovascular Surgeons of Asia·Hiroaki KomatsuNoritoshi Nishiyama
Oct 27, 2012·Tuberculosis and Respiratory Diseases·Yong Hwan AhnSang Hyun Park
Feb 24, 2017·Surgery Today·Haruhiko Nakamura, Toshihide Nishimura

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