Intraluminal brachytherapy in bile duct carcinomas

The Australian and New Zealand Journal of Surgery
J LeungR Das

Abstract

Cholangiocarcinoma of the biliary tract is a rare tumour which has been treated with surgery, radiotherapy, chemotherapy, bypass procedures and stenting. Surgery remains the only curative treatment for these tumours, but a large proportion are unresectable. Intraluminal brachytherapy has been reported as an effective treatment for localized cholangiocarcinoma of the biliary tract. The purpose of our study was to analyse the survival of patients with biliary tract carcinoma treated with iridium-192 brachytherapy. A retrospective review of patients treated at Peter MacCallum was undertaken. From 1989 to 1994, 16 patients underwent brachytherapy via transhepatic approach for cholangiocarcinoma. There were 12 male and four female patients. The median age was 65 (range 40-83). All patients had cholangiocarcinoma. Prior treatment included complete resection in three, partial resection in one, bypass procedures in eight, endoscopic stents in five and external biliary drainage in 15 of the 16 patients. One patient had received external beam irradiation. The median survival was 23 months and 61% survived 1 year. The most common acute complication was cholangitis seen in four patients and the most common late complications were duodenal ...Continue Reading

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Citations

Oct 23, 1998·Journal of the American College of Surgeons·S RoayaieM E Schwartz
Mar 11, 2005·Journal of Vascular and Interventional Radiology : JVIR·Ingrid BurgerJean-Francois H Geschwind
May 1, 1997·Australasian Radiology·J T Leung, R Kuan
Mar 16, 2007·Liver International : Official Journal of the International Association for the Study of the Liver·Virendra SinghSuresh C Sharma

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