Intraluminal brachytherapy in the treatment of pancreas and bile duct carcinoma

International Journal of Radiation Oncology, Biology, Physics
P MontemaggiP Marano

Abstract

A new method of palliation of malignant obstructive jaundice is presented. Twelve patients with carcinoma of the extrahepatic bile ducts (EHBD-five patients) or pancreatic head (PH-seven patients) received radiation therapy between 1988 and 1991. Percutaneous transhepatic biliary drainage was performed in four EHBD patients and an endoprosthesis was placed during endoscopic retrograde cholangiopancreatography (ERCP) in the other eight patients. All 12 received intraluminal brachytherapy (ILBT): 20-50 Gy calculated at 1 cm from the Iridium-192 (192Ir) wire. In four PH patients the source was placed in the duct of Wirsung; in the other eight patients ILBT was performed via the common bile duct. Five of the seven PH patients and one of the five EHBD patients received External Beam Radiation Therapy (EBRT): 26-50 Gy, alone or with concomitant 5-Fluorouracil (5-FU). Cholangitis occurred in six patients. Three PH patients treated with EBRT+ILBT developed gastrointestinal toxicities. With a minimum follow-up of 18 months, median survival times were 14 months (EHBD) and 11.5 months (PH); one of the seven PH patients is alive (29 months) and two of the EHBD patients are alive (18 and 43 months). All patients had satisfactory control of ...Continue Reading

References

Jun 1, 1978·Radiology·M V Pilepich, P M Lambert
Jan 1, 1990·International Journal of Radiation Oncology, Biology, Physics·B Veeze-KuijpersO T Terpstra
Jan 1, 1990·International Journal of Radiation Oncology, Biology, Physics·A D Treurniet-DonkerW L van Putten
May 1, 1990·International Journal of Radiation Oncology, Biology, Physics·B D MinskyD Nori
Jun 1, 1989·International Journal of Radiation Oncology, Biology, Physics·J E TepperA M Cohen
Feb 1, 1985·International Journal of Radiation Oncology, Biology, Physics·D W JohnsonD R Goffinet
Jan 1, 1989·International Journal of Radiation Oncology, Biology, Physics·F R BagneD G Bronn
Mar 1, 1989·Southern Medical Journal·W F Sindelar, T J Kinsella
Jan 1, 1989·Cancer Investigation·B D Minsky, A M Cohen
Nov 1, 1989·International Journal of Radiation Oncology, Biology, Physics·T PeretzM F Brennan
Feb 1, 1988·World Journal of Surgery·Y IwasakiA Nishimura
Sep 1, 1988·International Journal of Radiation Oncology, Biology, Physics·J K HayesF J Miller
Mar 1, 1987·International Journal of Radiation Oncology, Biology, Physics·J N Fields, B Emami
Jan 1, 1988·International Journal of Radiation Oncology, Biology, Physics·M MohiuddinF E Rosato
Feb 1, 1988·International Journal of Radiation Oncology, Biology, Physics·J Y WongJ D Beatty
Apr 1, 1985·International Journal of Radiation Oncology, Biology, Physics·B MittalS Iwatsuki
May 1, 1984·Southern Medical Journal·S NagR E Gold
Mar 1, 1983·Radiology·Y HishikawaY Imajyo
Nov 1, 1984·International Journal of Radiation Oncology, Biology, Physics·S J BuskirkJ K Martin
Dec 1, 1984·International Journal of Radiation Oncology, Biology, Physics·T D Fogel, J B Weissberg
Dec 1, 1984·World Journal of Surgery·R R Dobelbower, A J Milligan
Dec 1, 1984·World Journal of Surgery·W U ShipleyE L Orlow
Mar 16, 1984·Deutsche medizinische Wochenschrift·J PhillipM Classen
Apr 1, 1981·Radiology·A HerskovicK T Noell

❮ Previous
Next ❯

Citations

Nov 7, 2000·Journal of Surgical Oncology·P D GarnerP A Johnstone
Sep 13, 2012·Current Gastroenterology Reports·Halim Charbel, Firas H Al-Kawas
Nov 22, 2013·Current Gastroenterology Reports·Nabeel S Koro, Samer Alkaade
May 12, 2005·Gastroenterology·Konstantinos N Lazaridis, Gregory J Gores
Jul 4, 2002·International Journal of Radiation Oncology, Biology, Physics·Christopher H CraneNora A Janjan
Oct 19, 1999·International Journal of Radiation Oncology, Biology, Physics·H KurosakiY Tanaka
Feb 13, 2001·Critical Reviews in Oncology/hematology·P Montemaggi, P Guerrieri
Feb 24, 2001·American Journal of Clinical Oncology·R OveO Haluszka
Aug 8, 2006·Current Opinion in Gastroenterology·Prabhleen Chahal, Todd H Baron
May 1, 1997·Australasian Radiology·J T Leung, R Kuan
Feb 25, 2014·Surgical Oncology Clinics of North America·Albert Amini, T Clark Gamblin
May 30, 2006·Hematology/oncology Clinics of North America·Arthur Y HungLisa A Kachnic
Mar 15, 2006·Gastroenterology Clinics of North America·Douglas G Adler, Shehzad N Merwat
Feb 1, 2003·Acta medica Austriaca·Ramona MayerA Hackl
Feb 24, 2015·Digestive Diseases and Sciences·Reem Z SharaihaMichel Kahaleh
Sep 25, 2010·International Journal of Radiation Oncology, Biology, Physics·A Paiman GhafooriBrian G Czito
Jun 28, 2014·International Journal of Radiation Oncology, Biology, Physics·Yasuo YoshiokaUNKNOWN Japanese Radiation Oncology Study Group (JROSG)
Jul 13, 2016·Gastroenterology Research and Practice·Tomazo Antonio Prince FranziniEduardo Guimarães Hourneaux de Moura
May 27, 2005·World Journal of Gastroenterology : WJG·Siu-Yin ChanSheung-Tat Fan
Feb 13, 2015·Clinical Endoscopy·Jason RoqueKhean-Lee Goh
Nov 30, 2005·Current Treatment Options in Gastroenterology·Prabhleen Chahal, Todd H Baron
Jul 2, 2017·Lasers in Medical Science·Roberta ReaGuido Costamagna

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology
M MaheJ P Gerard
HPB Surgery : a World Journal of Hepatic, Pancreatic and Biliary Surgery
E R Lemmer, P C Bornman
© 2021 Meta ULC. All rights reserved