Intramedullary Masses of the Spinal Cord: Radiologic-Pathologic Correlation.

Radiographics : a Review Publication of the Radiological Society of North America, Inc
Robert Y Shih, K K Koeller

Abstract

Spinal cord tumors are a challenge for patients and neurosurgeons because of the high risk of neurologic deficits from the disease process and surgical interventions. Spinal cord tumors are uncommon, and approximately 2%-3% of primary intra-axial tumors of the central nervous system occur in the spinal cord. Primary intra-axial tumors are usually derived from neuroepithelial tissue, especially glial cells. This often leads to a classic intramedullary mass differential diagnosis of ependymoma or astrocytoma, which together constitute up to 70% of spinal cord tumors. For example, ependymomas occur predominantly in adults, and astrocytomas (specifically pilocytic astrocytomas) occur predominantly in children. While that is an excellent starting point, in order to refine the differential diagnosis, the authors review the radiologic-pathologic features of specific neoplastic categories and entities recognized by the World Health Organization (WHO) in the 2016 WHO Classification of Tumours of the Central Nervous System and a few additional congenital-developmental entities. Radiologists can add value by providing a reasonable preoperative differential diagnosis for the patient and neurosurgeon, in many cases by favoring the most comm...Continue Reading

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Citations

Jun 17, 2020·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Karen Buch
Oct 24, 2021·World Neurosurgery·Dragan JankovicKenan I Arnautovic

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